Results 51 to 60 of about 5,413 (203)

Cordycepin inhibits colon cancer proliferation by suppressing MYC expression

BMC Pharmacology and Toxicology, 2022
Background Cordycepin is a purine nucleoside anti-metabolite and anti-biotic isolated from the fungus Cordyceps militaris, which has potential anti-neoplastic activities. This study aimed to investigate the effect of cordycepin in inhibiting colon cancer
Zhe Zhang, Kui Li, Zhi Zheng, Yu Liu
doaj   +1 more source

Anticancer and Cardioprotective Properties of Medicinal Mushrooms: Current Evidence and Future Prospects

New Zealand Journal of Botany, Volume 64, Issue 3, September 2026.
Introduction: Cardiotoxicity is an undesirable side effect of chemotherapy that limits the effectiveness of cancer treatment. Almost all cardiotoxic agents cause cardiovascular complications, leading to oxidative stress and other pathological conditions.
Susanna Badalyan, Sylvie Rapior, Anush Barkhudaryan   +2 more
wiley   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, Volume 15, Issue 3, Page 206-226, September 2026.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Cordycepin affects growth factor-dependent gene expression [PDF]

, 2018
The natural compound cordycepin (3’-deoxyadenosine) causes a reduction in breast cancer cell viability. Microarray analysis showed that growth related genes are down-regulated by cordycepin.
Lin, Jialiang
core  

Dengue Virus Molecular Targets and Antiviral Drug Development: Advances, Challenges and Therapeutic Perspectives

ChemistrySelect, Volume 11, Issue 33, 1 September 2026.
This narrative review analyzes DENV molecular targets, including structural proteins (C, prM/M, E), non‐structural components (NS1NS5), and host factors, alongside small‐molecule candidates in preclinical and clinical phases. Owing to high structural conservation, the NS2B‐NS3 protease and NS5 (RdRp/MTase) remain primary drug discovery focuses, while ...
Aryane Lucia da Silva Aguiar De Oliveira, José Arion Da Silva Moura, Pedro César de Souza, Marcelo Arthur Dias da Costa Santana, Matheus Vinicius Guimarães de Melo, Douglas Carvalho Francisco Viana, Marina Galdino Da Rocha Pitta, Isabella Luiza Ralph de Oliveira, Maira Galdino Da Rocha Pitta   +8 more
wiley   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

Advanced Science, Volume 13, Issue 44, 7 August 2026.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu, Caiyan Lin, Lijie Zhang, Xue Jiang, Huawen Li, Yangzhe Wu   +5 more
wiley   +1 more source

Synchronization of MEL cell commitment with cordycepin

Cell, 1979
The response of differentiating MEL cells to the nucleotide analogue cordycepin reveals a previously unrecognized aspect of the molecular events which cause commitment of these cells to terminal erythroid differentiation. Cordycepin rapidly inhibits commitment of DMSO-treated MEL cells in a dose range which does not cause cytotoxicity.
R, Levenson, J, Kernen, D, Housman
openaire   +2 more sources

Cordyceps militaris Ethanol Extract Alleviates Hyperglycemia in Type 2 Diabetic Mice in Association With Gut Microbiota Modification

eFood, Volume 7, Issue 4, August 2026.
Cordyceps militaris ethanol extract (CME) shows potential for ameliorating glucose and lipid metabolism in T2DM mice. The improvements are correlated with the regulation of gut microbiota and increased short‐chain fatty acid levels, offering a novel perspective for future diabetes interventions.
Huanhuan Wen, Wenke Hu, Xinru Xu, Na Wu, Huangcong Ding, Haonan Wang, Xiaoyu Gao, Ligen Chen, Chao Zhao, Rong Shao, Wei Xu   +10 more
wiley   +1 more source

Cordycepin Induces Apoptosis and Inhibits Proliferation of Human Lung Cancer Cell Line H1975 via Inhibiting the Phosphorylation of EGFR

Molecules, 2016
Cordycepin is an active component of the traditional Chinese medicine Cordyceps sinensis and Cordyceps militaris with notable anticancer activity. Though the prominent inhibitory activity was reported in different kinds of cancer cell lines, the concrete
Zheng Wang, Xue Wu, Yan-Ni Liang, Li Wang, Zhong-Xing Song, Jian-Li Liu, Zhi-Shu Tang   +6 more
doaj   +1 more source

Rapid CO2 effects on protein‐related metabolism during photosynthetic gas exchange

The Plant Journal, Volume 127, Issue 1, July 2026.
SUMMARY It is common practice to vary atmospheric CO2 mole fraction (Ca) during gas exchange experiments to manipulate photorespiration and explore photosynthetic properties such as maximum carboxylation velocity. In doing so, it is assumed that changing Ca essentially alters the carboxylation‐to‐oxygenation ratio, with negligible effects on other ...
Corentin Dourmap, Cyril Abadie, Marlène Davanture, Willy Bienvenut, Julie Lalande, Guillaume Tcherkez   +5 more
wiley   +1 more source