Results 41 to 50 of about 5,413 (203)

Cordycepin and N6-(2-hydroxyethyl)-adenosine from Cordyceps pruinosa and their interaction with human serum albumin.

open access: yesPLoS ONE, 2015
Cordyceps pruinosa (CP) is often used as Traditional Chinese Medicine, but the substance basis of its medicinal properties is unclear. In this study, two compounds were isolated from CP cultures by column chromatography, and identified as cordycepin and ...
Zebin Meng   +4 more
doaj   +1 more source

Susceptibility of Trypanosoma evansi to cordycepin

open access: yesBiomedicine & Pharmacotherapy, 2011
Drugs, which are effective during the early stage of trypanosomosis, but poorly penetrate the blood-brain barrier, are ineffective when parasites reach the brain and cause encephalitis. In order to seek alternative treatments, the aim of this study was to test the susceptibility of T.
Aleksandro S, Da Silva   +10 more
openaire   +2 more sources

Studies on the synthesis and structure of cordycepin monophosphate [PDF]

open access: yesBiochimica et Biophysica Acta, 1963
SUMMARY Cordycepin monophosphate has been synthesized by two methods. One of these was chemical and involved treatment of cordycepin with cyanoethyl phosphate in the presence of N,N'-dicyclohexylcarbodiimide with subsequent alkaline hydrolysis. The other involved a phosphate transfer from uridine 5'-phosphate to cordycepin utilizing an enzyme prepared ...
Rottman, Fritz   +2 more
openaire   +5 more sources

Effects of cordycepin on the microglia-overactivation-induced impairments of growth and development of hippocampal cultured neurons. [PDF]

open access: yesPLoS ONE, 2015
Microglial cells are normally activated in response to brain injury or immunological stimuli to protect central nervous system (CNS). However, over-activation of microglia conversely amplifies the inflammatory effects and mediates cellular degeneration ...
Jie Peng   +4 more
doaj   +1 more source

Cordycepin Sensitizes Cholangiocarcinoma Cells to Be Killed by Natural Killer-92 (NK-92) Cells

open access: yesMolecules, 2021
Immunotherapy harnessing immune functions is a promising strategy for cancer treatment. Tumor sensitization is one approach to enhance tumor cell susceptibility to immune cell cytotoxicity that can be used in combination with immunotherapy to achieve ...
Suthida Panwong   +6 more
doaj   +1 more source

Bioactive compounds in insects—Composition, extraction, functionality, food applications, and safety concerns

open access: yesFood Biomacromolecules, EarlyView.
This review synthesizes 94 studies (2000–2025) exploring edible insects as sustainable sources of peptides, lipids, and chitin. Utilizing “green” extraction, these bioactives offer antioxidant and antimicrobial benefits for functional foods. However, addressing safety concerns like allergenicity and heavy metals through standardized frameworks remains ...
Blessing Rachael Adeyeye   +1 more
wiley   +1 more source

Anti‐inflammatory effects of cordycepin: A review

open access: yesPhytotherapy Research, 2020
Cordycepin is the major bioactive component extracted from Cordyceps militaris. In recent years, cordycepin has received increasing attention owing to its multiple pharmacological activities. This study reviews recent researches on the anti‐inflammatory effects and the related activities of cordycepin.
Tan, Lu   +9 more
openaire   +2 more sources

Cordycepin and the entomopathogenic fungus Cordyceps militaris [PDF]

open access: yes, 2022
Cordyceps militaris is a widespread entomopathogenic fungus found in Europe, Asia, and North America, with a large number of insect hosts, predominantly lepidopteran larvae (caterpillars).
Wellham, Peter A D
core  

Improved Cordycepin Production by Cordyceps militaris KYL05 Using Casein Hydrolysate in Submerged Conditions

open access: yesBiomolecules, 2019
Cordycepin, a beneficial bioactive product specifically found in Cordyceps, has received attention in various bioindustrial applications such as in pharmaceuticals, functional foods, and cosmetics, due to its significant functions.
Soo Kweon Lee   +7 more
doaj   +1 more source

Cordycepin Alleviates Non Alcoholic Fatty Liver Disease Progression by Stabilizing GCH1 to Inhibit Ferroptosis

open access: yesPhytotherapy Research, EarlyView.
COR stabilizes GCH1 and inhibits ferroptosis. ABSTRACT To investigate the effects and targets of cordycepin (COR) in alleviating non‐alcoholic fatty liver disease (NAFLD). High‐fat diet was used to induce NAFLD in mice, and after COR gavage administration, changes in liver function, glucose and lipid metabolism, and ferroptosis‐related signaling were ...
Chenyang Han   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy