Results 41 to 50 of about 15,220 (224)

Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis

Scientific Reports, 2022
Ectopic ceramide accumulation in insulin-responsive tissues contributes to the development of obesity and impairs insulin sensitivity. Moreover, pharmacological inhibition of serine palmitoyl transferase (SPT), the first enzyme essential for ceramide ...
Ying Li, Chad Lamar Talbot, Bhawna Chandravanshi, Alec Ksiazek, Ayushi Sood, Kamrul Hasan Chowdhury, J. Alan Maschek, James Cox, Adhini Kuppuswamy Satheesh Babu, Henry A. Paz, Pon Velayutham Anandh Babu, David K. Meyerholz, Umesh D. Wankhade, William Holland, E. Shyong Tai, Scott A. Summers, Bhagirath Chaurasia   +16 more
doaj   +1 more source

Development of cordycepin formulations for preclinical and clinical studies [PDF]

, 2017
There is extensive literature on in vivo studies with cordycepin but these studies were generally conducted without validation of the various formulations, especially in terms of the solubility of cordycepin in the dosing vehicles used.
A Kondrashov, A Sato, AM Sugar, BS Pan, C Dou, Cecilia Adrower, Chaolong Qin, Cornelia H. de Moor, CR Hind, DF Nickerson, DW Zhang, EA Thackaberry, F Wang, HG Kim, HJ Cho, HP Wei, HS Tuli, HS Tuli, HS Yoo, J Wong, J Yuan, Jong Bong Lee, JV Julian-Ortiz de, JW Jeong, JW Jeong, K Nakamura, K Nakamura, KJ Won, L Ma, MA Cho, ME Rottenberg, N Yoshikawa, Pavel Gershkovich, Peter M. Fischer, PV Turner, PV Turner, R Ikeda, R Skeist, S Patel, S Shin, SF Leu, XX Zhou, XX Zhou, Y Du, Y Sun, YJ Tsai, YR Lee, YY Wong, Z Cheng, Z Hu, Z Tianzhu, ZL Cai   +51 more
core   +2 more sources

CYP52X1, representing new cytochrome P450 subfamily, displays fatty acid hydroxylase activity and contributes to virulence and growth on insect cuticular substrates in entomopathogenic fungus Beauveria bassiana [PDF]

, 2012
Infection of insects by the entomopathogenic fungus Beauveria bassiana proceeds via attachment and penetration of the host cuticle. The outermost epicuticular layer or waxy layer of the insect represents a structure rich in lipids including abundant ...
Bernard, Grausem, Keyhani, Nemat O., Lesot, Agnes, Pedrini, Nicolás, Pinot, Franck, Widemann, Emilie, Zhang, Shizhu   +6 more
core   +2 more sources

Cordyceps cicadae induces G2/M cell cycle arrest in MHCC97H human hepatocellular carcinoma cells: a proteomic study [PDF]

, 2014
published_or_final_versio
Lee, CYJ, Sit, WH, Wan, JMF, Wang, H, Zhang, J   +4 more
core   +6 more sources

Survey analysis of soil physicochemical factors that influence the distribution of Cordyceps in the Xiahe Region of Gansu Province

Open Life Sciences, 2017
In this paper, we studied the influence of soil physicochemical factors on the distribution of Cordyceps. We found that in the soil layers at different depths, the differences in pH values, total N (TN), total P (TP), available P (AP) and available K (AK)
He Shuling, Ma Lingfa, Zhao Kentian, Yang Jingjun, Chang Yuwei   +4 more
doaj   +1 more source

Structural characterization of an α-1, 6-linked galactomannan from natural Cordyceps 2 sinensis [PDF]

, 2018
An α-1, 6-linked galactomannan was isolated and purified from natural Cordyceps sinensis. The fine structure analysis of this polysaccharide was elucidated based on partial acid hydrolysis, monosaccharide composition, methylation and 1D/2D nuclear ...
Chen, Shuping, Cui, Steve W., Li, Yajing, Nie, Shaoping, Phillips, Aled O., Phillips, Glyn O., Wang, Junqiao, Xie, Mingyong   +7 more
core   +2 more sources

Optimization of protein extraction and two-dimensional gel electrophoresis profiles for the identification of Cordyceps sinensis and other similar species. [PDF]

PLoS ONE, 2018
Given that Chinese materia medica (CMM) is expensive and rare, people take tremendous risk to adulterate and falsify Cordyceps sinensis with counterfeit species with similar morphological features.
Roy Chi Ho Chan, Steven Sai Wo Lam, Fiona Long Yan Fong, Dominic Tak Wah Chan, Fred Wang Fat Lee, Eric Tung Po Sze   +5 more
doaj   +1 more source

Bitter Melon Polysaccharides Enhance Goblet Cell Function and Mucosal Integrity in DSS‐Induced Colitis Through Microbiota Remodeling

Food Bioengineering, EarlyView.
ABSTRACT Bitter melon polysaccharides (BMPs), a key bioactive component of bitter melon, exhibit a range of biological activities including gut microbiota regulation, immune modulation, and antioxidant activity. Based on previous evidence of its protective effect on the colonic mucus barrier under high‐fat‐diet condition, this study evaluated the ...
Tangying Kang, Yiming Zhu, Jiaxuan Zhu, Meiling Xiao, Yansheng Zhao, Ying Zhu, Xiang Xiao   +6 more
wiley   +1 more source

Characterization of Metabolite Landscape Distinguishes Medicinal Fungus Cordyceps sinensis and other Cordyceps by UHPLC-Q Exactive HF-X Untargeted Metabolomics

Molecules, 2023
Cordyceps represent a valuable class of medicinal fungi with potential utilization. The overexploitation and resource scarcity of Cordyceps sinensis (CS) have led to the emergence of Cordyceps such as Cordyceps militaris (CM) and Cordyceps cicadae (CC ...
Chuyu Tang, Xiuzhang Li, Tao Wang, Jie Wang, Mengjun Xiao, Min He, Xiyun Chang, Yuejun Fan, Yuling Li   +8 more
doaj   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source