Results 81 to 90 of about 3,197,364 (211)

Copper isotope evidence for large-scale sulphide fractionation during Earth’s differentiation [PDF]

, 2015
The differentiation of Earth into a metallic core and silicate mantle left its signature on the chemical and isotopic composition of the bulk silicate Earth (BSE).
Savage, P.S., Siebert, J., Badro, J., Moynier, F., Puchtel, I.S., Chen, H., Savage, Paul S., Shofner, G.   +7 more
core   +1 more source

The Making of Forum Ware: A High‐Resolution Archaeometric Study of Early Medieval Glazed Pottery From the Templum Pacis (Imperial Forum, Rome)

Archaeometry, EarlyView.
ABSTRACT The object of this study consists of an archaeometric investigation of Early medieval Forum Ware glazed ceramics found in the central archaeological area of Rome, a significant chronological and economic marker for 8th–11th centuries. Instrumental analysis included digital microscopy, ESEM‐EDS imaging, EDS spectral analysis, EMPA quantitative ...
Martina Bernardi, Simona Boccuti, Emiliano Di Luzio   +2 more
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

FeO Content of Earth’s Liquid Core

Physical Review X, 2019
The standard model of Earth’s core evolution has the bulk composition set at formation, with slow cooling beneath a solid mantle providing power for geomagnetic field generation.
Monica Pozzo, Chris Davies, David Gubbins, Dario Alfè   +3 more
doaj   +1 more source

A generating process of geomagnetic drifting field

Earth, Planets and Space, 2018
The geomagnetic field is comprised of drifting and standing fields. The drifting field has two remarkable features. One is predominance of sectorial harmonics when the field is expressed in a spherical harmonic series, and the other is uniform drift rate
Takesi Yukutake, Hisayoshi Shimizu
doaj   +1 more source

Contrasting Food Web Dynamics Across Oceanographic Boundaries in Subarctic Pelagic Ecosystems

Fisheries Oceanography, EarlyView.
ABSTRACT Understanding the structure of pelagic food webs across multiple trophic levels is critical for elucidating species interactions, energy flow, and anthropogenic impacts on production. This study presents a comprehensive analysis of the eastern North Pacific pelagic food webs, focusing on the Gulf of Alaska (GoA) during late winter of 2019.
Genyffer C. Troina, Evgeny A. Pakhomov, Laurie Weitkamp, Brian P. V. Hunt   +3 more
wiley   +1 more source

Thermal, Elastic and Seismic Signature of High-Resolution Mantle Circulation Models [PDF]

, 2009
A long-standing question in the study of Earth’s deep interior is the origin of seismic mantle heterogeneity. The challenge is to efficiently mine the wealth of information available in complex seismic waveforms and to separate the potential ...
Schuberth, Bernhard
core   +1 more source

The Influence of ɛ‐to‐Py FeOOH Phase Transition on the Lower Mantle Heterogeneities

Geochemistry, Geophysics, Geosystems
Hydrous minerals transported by cold subducting slabs to the lowermost mantle are believed to significantly influence mantle properties and the heterogeneities in the core‐mantle boundary (CMB) region.
Sparsh Sharma, Gaurav Shukla
doaj   +1 more source