Results 101 to 110 of about 28,187 (286)

Doing research on the effectiveness of psychotherapy and psychotherapy training: a person-centered/experiential perspective [PDF]

open access: yes, 2006
In this article, we present a framework for selecting instruments for evaluating psychotherapy and psychotherapy training from a person-centered and experiential psychotherapy (PCEP) perspective.
Elliott, Robert, Zucconi, Alberto
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Structural insights into the mechanism of a novel protein targeting pathway in Gram‐negative bacteria

open access: yesFEBS Open Bio, 2020
Many nascent polypeptides synthesized in the cytoplasm are translocated across membranes via a specific ‘translocon’ composed of protein complexes. Recently, a novel targeting pathway for the outer membrane β‐barrel proteins (OMPs) in Gram‐negative ...
Feng Jin
doaj   +1 more source

Protocol for the Mindful Student Study: a randomised controlled trial of the provision of a mindfulness intervention to support university students' well-being and resilience to stress. [PDF]

open access: yes, 2016
INTRODUCTION: Levels of stress in UK university students are high, with an increase in the proportion of students seeking help in recent years. Academic pressure is reported as a major trigger.
Benton, Alice   +8 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The Clinical Outcomes in Routine Evaluation-Outcome Measure

open access: yesRevista Brasileira de Psicodrama, 2019
Latin American mental health services are moving from the psychiatric hospital model to a community-based model. The effectiveness of these new services needs to be evaluated and that can be done through routine outcome monitoring.
Clara Paz, Chris Evans
doaj  

Hollow-core infrared fiber incorporating metal-wire metamaterial [PDF]

open access: yes, 2009
Infrared (IR) light is considered important for short-range wireless communication, thermal sensing, spectroscopy, material processing, medical surgery, astronomy etc.
Mortensen, Niels Asger, Yan, Min
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Using Rasch analysis to form plausible health states amenable to valuation: the development of CORE-6D from CORE-OM in order to elicit preferences for common mental health problems

open access: yes, 2001
Purpose: To describe a new approach for deriving a preference-based index from a condition specific measure that uses Rasch analysis to develop health states.
Mavranezouli, I.   +3 more
core  

Investigating invariant item ordering in the Mental Health Inventory : an illustration of the use of different methods [PDF]

open access: yes, 2014
Invariant item ordering is a property of scales whereby the items are scored in the same order across a wide range of the latent trait and across a wide range of respondents.
Meijer, Rob R.   +3 more
core   +2 more sources

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