Results 231 to 240 of about 28,187 (286)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Clinical effectiveness of the Circle of Security-Parenting group intervention for birthing parents in perinatal mental health services in England (COSI): a pragmatic, multicentre, assessor-masked, randomised controlled trial.

Lancet Psychiatry
Rosan C, Alyousefi-van Dijk K, Cornelius V, Waddingham E, Darwin Z, Babalis D, Richards L, Hopson H, Pilling S, Fearon P, Deighton J, Pizzo E, Fonagy P.   +12 more
europepmc   +1 more source

Wrapping a single crystal spin-crossover complex with a single crystal non-spin-crossover complex to modulate the spin-transition temperature. [PDF]

Chem Sci
Fukui T, Tsuchiya M, Mita N, Fukushima T.   +3 more
europepmc   +1 more source

Metadatastandaarden, Dublin Core en het gelaagd metadatamodel [PDF]

, 2010
Coppens, Sam, Haspeslagh, Jan, Hochstenbach, Patrick, Mannens, Erik, Van de Walle, Rik, Van Nieuwerburgh, Inge   +5 more
core  

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Bioengineering methods for tailoring treatment of Osteomyelitis: Advancing strategies and application. [PDF]

Mater Today Bio
Geng QR, Li YX, Gong H, Gan TJ, Yin SJ, Ma XK, Zheng C, Wu Y, Zhang H, Wang Y.   +9 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Genesis Mechanism of Low Resistivity in the Lower Cambrian Qiongzhusi Formation Shale and Its Response Characteristics to Pore Structure - Take the Z201 Well as an Example. [PDF]

ACS Omega
Liang F, Zhao Q, Zhao S, Shi Z, Zhang Q, Zhou T, Wang Y, Cui H, Chen H, Wang Y.   +9 more
europepmc   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Spatial patterns and prognostic relevance of CD1a⁺ immature and CD208⁺ mature dendritic cells in colorectal cancer from non-tumor adjacent mucosa to liver metastases. [PDF]

Cancer Immunol Immunother
Pavlov S, Ali E, Ye W, Červenková L, Ambrozkiewicz F, Vyčítal O, Daum O, Liška V, Hemminki K, Trailin A.   +9 more
europepmc   +1 more source