How should we evaluate research on counselling and the treatment of depression? A case study on how NICE’s draft 2018 guideline considered what counts as best evidence [PDF]
Background: Health guidelines are developed to improve patient care by ensuring the most recent and “best available evidence” is used to guide treatment recommendations (NICE Guidance, 2017).
Barber +74 more
core +2 more sources
Versão Portuguesa do CORE-OM: tradução, adaptação e estudo preliminar das suas propriedades psicométricas [PDF]
CONTEXTO: O Clinical Outcome Routine Evaluation - Outcome Measure (CORE-OM) e um instrumento europeu de autorrelato para medir a saude mental em adultos e se encontra adaptado para mais de 20 paises. O CORE-OM e utilizado em contextos clinicos hospitalares, saude ocupacional e educacional, assim como na avaliacao da qualidade dos servicos de saude ...
Sales, Célia Maria Dias +3 more
openaire +4 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The integration of human resource and operation management practices and its link with performance: A longitudinal latent class study [PDF]
This paper reviews the literature on the association between lean production and performance. From this, propositions on the integration and evolution of operation and human resource management practices associated with the lean production concept are ...
Abdi +101 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Efficacy of Psychological Treatments of Students at the University of Rijeka
The main goal of the study was to evaluate psychological treatments of students at the University Counseling Center in Rijeka. The second goal was to check the usefulness of CORE-OM questionnaire as a measure for treatment changes. Of all the students at
Ines Jakovčić +2 more
doaj
Organic coating on sulfate and soot particles during late summer in the Svalbard Archipelago [PDF]
Interaction of anthropogenic particles with radiation and clouds plays an important role in Arctic climate change. The mixing state of aerosols is a key parameter to influence aerosol radiation and aerosol–cloud interactions.
H. Yu +11 more
doaj +1 more source
Implementation of routine outcome measurement in child and adolescent mental health services in the United Kingdom: a critical perspective [PDF]
The aim of this commentary is to provide an overview of clinical outcome measures that are currently recommended for use in UK Child and Adolescent Mental Health Services (CAMHS), focusing on measures that are applicable across a wide range of conditions
A Willis +40 more
core +2 more sources
Examining response shifts in the Clinical Outcomes in Routine Evaluation- Outcome Measure (CORE-OM) [PDF]
Response shifts can be defined as a change in the way that a respondent interprets and responds to symptom questionnaire items, over and above true changes in their symptoms. Response shifts are liable to occur as a result of psychotherapy and can undermine evaluations of the effectiveness of psychotherapy interventions by making pre- and post ...
Murray, Aja +3 more
openaire +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source

