Results 151 to 160 of about 835 (252)

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

open access: yesBrain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen   +8 more
wiley   +1 more source

Scalable Mie-Silk textile for dual-mode personal cooling indoors and outdoors. [PDF]

open access: yesSci Adv
Wang Y   +16 more
europepmc   +1 more source

Implementing Design Thinking in Early‐Stage Start‐Up Innovation Processes: The Case of MedTech/HealthTech Sector

open access: yesCreativity and Innovation Management, EarlyView.
ABSTRACT Although the value of design thinking (DT) in the innovation processes of large organisations is widely examined within the literature, its role and value for early‐stage start‐up innovation processes remains less well understood. This study investigates how start‐up founders implement DT practices in the early‐stage start‐up innovation ...
Rojeanne Stoffer   +2 more
wiley   +1 more source

Processionary Moth Exposure in Europe: Toxic–Irritant and Immunoglobulin E‐Mediated Endotypes, Diagnosis and Management

open access: yesClinical &Experimental Allergy, EarlyView.
Most reactions are toxic–irritant, driven by epithelial injury and neuro‐inflammatory activation. IgE‐mediated allergy is less common but may cause immediate systemic reactions. Endotype differentiation guides diagnosis, risk stratification and management.
Prasad Dasari   +9 more
wiley   +1 more source

Supervision as a Dispersed Practice: Exploring the Creation of Supervisory Spaces in Day‐to‐Day Social Work Practice

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT Supervision is integral to social work practice; however, how it operates in day‐to‐day practice remains poorly understood. Existing research mainly comprises quantitative and qualitative accounts of social workers' and supervisors' experiences of supervision.
Mark Gregory
wiley   +1 more source

Shifu-Inspired Fungal Paper Yarns. [PDF]

open access: yesAdv Sci (Weinh)
Zhao A, Jones MP, Weiland K, Bismarck A.
europepmc   +1 more source

Progressively Projected Newton's Method

open access: yesComputer Graphics Forum, EarlyView.
Abstract Newton's Method is widely used to find the solution of complex non‐linear simulation problems. To guarantee a descent direction, it is common practice to clamp the negative eigenvalues of each element Hessian prior to assembly—a strategy known as Projected Newton (PN)—but this perturbation often hinders convergence.
J. A. Fernández‐Fernández   +2 more
wiley   +1 more source

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