Results 141 to 150 of about 3,820,570 (317)
Fall 2015 Core Assessment Overall Report
, 2015 This overall report for Wright State University contains data across all 14 course sections that were part of the Fall 2015 Core ...
Wright State University
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Spring 2016 Core Assessment Overall Report
, 2016 This report contains data across all seven Wright State University course sections that were part of the Spring 2016 Core ...
Wright State University
core
EC 2000 Economic Life Core General Education Assessment, 2021-2022
, 2022 This report assesses Wright State University\u27s course EC 2000, Economic Life, as part of the institution’s ongoing general education Core assessment ...
Raj Soin College of Business, Wright State University
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
STT 2640 Elementary Statistics Core General Education Assessment, 2019-2020
, 2020 This report assesses Wright State University\u27s course STT 2640, Elementary Statistics, as part of the institution’s ongoing general education Core assessment ...
College of Science and Mathematics, Wright State University
core
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
ML 2050 Russian Culture Core General Education Assessment, 2017-2018
, 2018 This report assesses Wright State University\u27s course ML 2050, Russian Culture, as part of the institution’s ongoing general education Core assessment ...
College of Liberal Arts, Wright State University
core