Results 61 to 70 of about 3,820,570 (317)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Genus Scleria in Colombia The Genus Scleria in Colombia
Since the publication of my revision of the American species of the genus Scleria (*), continued field work and herbarium studies have brought to light numerous new distributional records for Colombia. In particular, the explorations of Dr.
Core Earl L.
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Mary Beard y los dioses propicios
Mary Beard y los dioses ...
Coré Ferrer Alcantud
doaj
A Note on the Core of TU-cooperative Games with Multiple Membership Externalities
A generalization of transferable utility cooperative games from the functional forms introduced by von Neumann and Morgenstern (1944, Theory of Games and Economic Behavior) and Lucas and Thrall (1963, Naval Research Logistics Quarterly, 10, 281–298) is ...
Heinrich H. Nax
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Element 2 AACU Math Literacy Rubric Core General Education Assessment, 2019-2020
The AACU Math Literacy Rubric for Element 2 - Mathematics as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core
Core Stability and Core Selection in a Decentralized Labor Matching Market
We propose a dynamic model of decentralized many-to-one matching in the context of a competitive labor market. Through wage offers and wage demands, firms compete over workers and workers compete over jobs. Firms make hire-and-fire decisions dependent on
Heinrich H. Nax, Bary S. R. Pradelski
doaj +1 more source
The article discusses the concepts of upscaling, the representative volume element (RVE) of the geological environment in relation to porosity from the point of view of the theory of structured continuum.
Damir I. Khassanov, Marat A. Lonshakov
doaj +1 more source

