Simulated microgravity models sex differences in knee osteoarthritis through a CD36-regulated mechano-metabolic circuit. [PDF]
Ma Z +9 more
europepmc +1 more source
Biomaterial design strategies for enhancing mitochondrial transplantation therapy
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source
The Mediator Complex: From Transcriptional Regulation to Disease Pathogenesis. [PDF]
Iyer S, Ito T, Nakagawa T, Hattori N.
europepmc +1 more source
Enhanced strategies for cuproptosis‐like death in bacterial infection treatment
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang +7 more
wiley +1 more source
Plasma Proteomic Profiling Identifies a Six-Protein Panel for Grading and Predicting Intervertebral Disc Degeneration. [PDF]
Zhou Z +8 more
europepmc +1 more source
Machine Learning Paradigm for Advanced Battery Electrolyte Development
Electrolyte materials determine ion transport kinetics within the bulk and interphases, ultimately influencing the performance of battery systems. As data‐driven paradigms increasingly reshape materials discovery, this review provides an application‐oriented exploration of the intersection between machine learning and electrolyte science. By evaluating
Chang Su +4 more
wiley +1 more source
Low LAMA2 expression may affect drug resistance and prognosis in ovarian cancer via positive LGR5 coexpression. [PDF]
Du Z +7 more
europepmc +1 more source
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik +3 more
wiley +1 more source
Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns. [PDF]
Kamei KF +5 more
europepmc +1 more source

