Results 181 to 190 of about 193,524 (221)

Metabolic plasticity in pancreatic ductal adenocarcinoma progression and response to treatment. [PDF]

Mol Cancer
Ma J, Bhardwaj V, Lobie PE, Pandey V.
europepmc   +1 more source

Mutation type‐specific transcriptomic signatures and readthrough therapy rescue in SMC1A‐related developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to investigate the molecular consequences of pathogenic variants in the SMC1A gene—particularly those associated with developmental and epileptic encephalopathy (DEE85)—and to evaluate the therapeutic potential of ataluren in restoring SMC1A function and mitigating disease‐related transcriptomic and genomic ...
Maddalena Di Nardo, Francesca Sardina, Maria M. Pallotta, Iñigo Marcos‐Alcalde, Paulino Gómez‐Puertas, Cinzia Rinaldo, Ian D. Krantz, Antonio Musio   +7 more
wiley   +1 more source

Integrin β3: structural functions, tumour microenvironment regulatory roles and targeted intervention strategies. [PDF]

Front Immunol
Peng L, Liu F, Yang Y, Zhang L, Huang S, Zhao F, Li C, Huang J, Wang Z, He J.   +9 more
europepmc   +1 more source

Iwr1 directs RNA polymerase II nuclear import [PDF]

, 2011
Czeko, Elmar
core  

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Impact of SliP4 deletion on the high-light acclimation in Synechocystis sp. PCC 6803. [PDF]

Microlife
Alvarenga-Lucius L, Maaß S, Reimann V, Becher D, Hess WR, Hagemann M.   +5 more
europepmc   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Network pharmacology, machine learning, and experiments uncover β-sitosterol targeting HSP90AA1 in medicinal-edible black soybean against aging. [PDF]

Front Med (Lausanne)
Jia Y, Yang J, Chen Q, Yang Y, Min W, Luo D.   +5 more
europepmc   +1 more source

Cuproptosis‐Related Genes in Immune Infiltration and Diagnosis in Hepatitis B Virus‐Related Acute Liver Failure

Exploration, EarlyView.
The role of cuproptosis in HBV‐ALF was explored via bioinformatics and liver biopsy tissues. There are some crosstalks among cuproptosis, immune infiltration, and ferroptosis (The figure was created by Bio Render). ABSTRACT Hepatitis B virus (HBV) infection poses a significant challenge to global health, particularly in developing countries such as ...
Jingwen Deng, Tao Zhu, Yueyang Wang, Sitong Zhang, Hong Deng, Guilan Quan, Tingting Peng, Chuanbin Wu, Huiqiang Cai, Chao Lu, Xiaopeng Cai   +10 more
wiley   +1 more source

Prediction of Targets and Mechanisms of Top Ten Core "Food-Medicine Homologous Traditional Chinese Medicines" in Delaying Vascular Aging: An Integrative Computational Study. [PDF]

Pharmaceuticals (Basel)
Bai Y, Liu Q, Zhou Q, Xiao P, Xia L.
europepmc   +1 more source