Results 221 to 230 of about 240,084 (355)

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

Advanced Science, EarlyView.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong, Di Wang, Haoze Song, Ting Sun, Yanhong Zhao, Wenjing Gu, Lexuan Lin, Yitong Zhao, Yipeng Liang, Xu Jin, Rongfeng Fu, Mankai Ju, Jie Gao, Jinfa Ma, Chengjie Gao, Anqi Zhang, Zhijian Xiao, Erlie Jiang, Renchi Yang, Shihui Ma, Lei Zhang, Lihong Shi   +21 more
wiley   +1 more source

Clinically guided core biopsy and cutaneous punch biopsy in the evaluation of breast lesions: a necessary test or an obsolete skill? [PDF]

Ir J Med Sci, 2023
Alameer A, Common M, Elwahab SA, Boland M, Allen M, Power C, Hambly N, Kerr J, Ni Mhuircheartaigh N, Staunton M, Hill ADK, Duke D.   +11 more
europepmc   +1 more source

Synchronous microwave ablation followed by core‐needle biopsy via a coaxial cannula for highly suspected malignant lung ground‐glass opacities: A single‐center, single‐arm retrospective study

, 2021
Fanlei Kong, Zhi‐Xin Bie, Yuanming Li, Bin Li, Run‐Qi Guo, Cheng-En Wang, Jin-Zhao Peng, Sheng Xu, Xiaoguang Li   +8 more
openalex   +1 more source

CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target

Advanced Science, EarlyView.
CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo, Xiaomeng Jia, Shenghong Wang, Xinyu Li, Yajing Liu, Lisen Lin, Zhengkun Wang, Fujun Liu, Slawomir Wolczynski, Nafis Rahman, Jie Gao, Xuguang Du, Suk‐Ying Tsang, Jiali Liu, Wei Song, Xiangdong Li   +15 more
wiley   +1 more source

Predicting nodal response to neoadjuvant treatment in breast cancer with core biopsy biomarkers of tumor microenvironment using data mining. [PDF]

Breast Cancer Res Treat
Pislar N, Gasljevic G, Matos E, Pilko G, Zgajnar J, Perhavec A.   +5 more
europepmc   +1 more source

ASO Author Reflections: Molecular Testing in Breast Cancer: Is Core Biopsy Equivalent to Surgical Specimen? [PDF]

Ann Surg Oncol, 2022
Orozco JIJ, Grumley JG.
europepmc   +1 more source

Core Biopsy of Pancreas [PDF]

, 2020
openaire   +1 more source

Limited value of adjunct fine-needle aspiration with percutaneous core biopsy of musculoskeletal tumors.

, 2014
A. I. K. McGow, H. K. Lee, Brenda Farnquist, David J. Lerner   +3 more
openalex   +1 more source

Evaluation of Newly Adapted Clip Marker System in Ultrasound-Guided Core Needle Biopsy for Suspicion of Breast Cancer [PDF]

, 2013
Rüdiger Schulz‐Wendtland, Peter Dankerl, G. Dilbat, M. Bani, P. Fasching, Katharina Heusinger, Michael P. Lux, Christian R. Loehberg, Sebastian M. Jud, Claudia Rauh, Christian Bayer, Matthias W. Beckmann, Michael Uder, M. Meier-Meitinger, Barbara Brehm   +14 more
openalex   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

Advanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu, Tan Wu, Larry Tso‐Lun Lo, Chi‐Chiu Ko, Xin Wang, Chi Him Eddie Ma   +5 more
wiley   +1 more source