Results 231 to 240 of about 240,084 (355)

Interferon‐Driven Biomarkers and Synergistic Therapy for PRMT5 Inhibition in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Triple‐negative breast cancer exhibits variable sensitivity to PRMT5 inhibition. Basal interferon signaling is identified as a key biomarker of response. PARP inhibition with olaparib induces IFN signaling, sensitizing resistant TNBC cells to PRMT5 inhibitors.
Ziwen Zhang   +9 more
wiley   +1 more source

Evaluation of an ultrasound-guided freeze-core biopsy system for canine and feline brain tumors. [PDF]

open access: yesFront Vet Sci
Adams BS   +7 more
europepmc   +1 more source

Ultrasound-guided core biopsy in the diagnosis of parotid neoplasia: an overview and update with a review of the literature. [PDF]

open access: yesBr J Radiol, 2022
Hurry KJ   +7 more
europepmc   +1 more source

Core Needle Biopsy Of Periacetabular Chondrosarcoma Often Results In Undergrading But Does Not Change Management By Experienced Orthopaedic Oncologists [PDF]

open access: gold
Hayden Harvard   +6 more
openalex   +1 more source

Muscle Organoids Reveal Exercise‐Like Contractions Rapidly Promote Muscle Health Via Lamtor1's Signaling to Both AMPK and mTOR

open access: yesAdvanced Science, EarlyView.
This study develops a novel 3D human skeletal muscle organoid platform to study the immediate molecular effects of exercise‐like contractions. The model uncovers rapid proteomic and transcriptomic responses, resolving a fundamental paradox by demonstrating how exercise‐induced Lamtor1 coordinately activates both AMPK and mTORC1. Lamtor1 is a compelling
Ziyue Yao   +9 more
wiley   +1 more source

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