Results 81 to 90 of about 3,062,730 (403)

Accuracy of elastic fusion biopsy in daily practice: results of a multicenter study of 2115 patients [PDF]

, 2018
OBJECTIVES: To assess the accuracy of Koelis fusion biopsy for the detection of prostate cancer and clinically significant prostate cancer in the everyday practice.
Albisinni S, Altobelli E, Baco E, Beatrici V, Cantiani A, Carbone A, Ciccariello M, Descotes JL, Dubreuil-Chambardel M, Eldred-Evans D, Fasolis G, Ferriero M, Fiard G, Forte V, Giacobbe A, Gontero P., Kumar P, Lacetera V, Marra G, Mozer P, Muto G, Oderda M, Papalia R, Pastore A, Peltier A, Piechaud T, Roche JB, Roupret M, Rouviere O, Simone G, Van Velthoven R   +30 more
core   +1 more source

Ki67 proliferation in core biopsies versus surgical samples - a model for neo-adjuvant breast cancer studies

BMC Cancer, 2011
Background An increasing number of neo-adjuvant breast cancer studies are being conducted and a novel model for tumor biological studies, the "window-of-opportunity" model, has revealed several advantages. Change in tumor cell proliferation, estimated by
Ingvar Christian, Loman Niklas, Klintman Marie, Bendahl Pär-Ola, Romero Quinci, Rydén Lisa, Rose Carsten, Grabau Dorthe, Borgquist Signe   +8 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Does shear wave ultrasound independently predict axillary lymph node metastasis in women with invasive breast cancer? [PDF]

, 2013
Shear wave elastography (SWE) shows promise as an adjunct to greyscale ultrasound examination in assessing breast masses. In breast cancer, higher lesion stiffness on SWE has been shown to be associated with features of poor prognosis.
A Evans, A Evans, AK Witkiewicz, Alastair Thompson, AM O’Shea, Andrew Evans, C Hatzis, CA Purdie, Caroline O. Michie, Colin A. Purdie, D Regner, DO Cosgrove, ES Burnside, J Boughey, JH Youk, JL Vandergrift, JLB Bevilacqua, JM Chang, Kim Thomson, KR Levental, LC Chen, Lee B. Jordan, MW Conklin, N Houssami, National Research Ethics Service, NO Kandemir, P Farmer, Patsy Whelehan, Petra Rauchhaus, PF Qiu, PL Fitzgibbons, Sarah Vinnicombe, T Kuehn, TC Kwok, WA Berg   +34 more
core   +4 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Focused ultrasound-enabled brain tumor liquid biopsy [PDF]

, 2018
Although blood-based liquid biopsies have emerged as a promising non-invasive method to detect biomarkers in various cancers, limited progress has been made for brain tumors.
Chen, Hong, Cheng, Galen, Dunn, Gavin P., Leuthardt, Eric C., Liu, Weijun, Nazeri, Arash, Petti, Allegra A., Wang, Xiaowei, Ye, Dezhuang, Yue, Yimei, Zhu, Lifei   +10 more
core   +3 more sources

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

A national registry for juvenile dermatomyositis and other paediatric idiopathic inflammatory myopathies: 10 years' experience; the Juvenile Dermatomyositis National (UK and Ireland) Cohort Biomarker Study and Repository for Idiopathic Inflammatory Myopathies [PDF]

, 2011
Objectives: The paediatric idiopathic inflammatory myopathies (IIMs) are a group of rare chronic inflammatory disorders of childhood, affecting muscle, skin and other organs.
Bohan, Bohan, Brown, Chinoy, Chinoy, Christen-Zaech, Clarissa A. Pilkington, Constantin, Elst, Gunawardena, Gunawardena, Huber, Huber, Huber, Huber, Isenberg, Joyce E. Davidson, Kevin Murray, Kim, Li, Li, Lovell, Lowry, Lucy R. Wedderburn, Maillard, Maillard, Marhaug, McCann, McCann, McCann, Mendez, Miller, Neil Martin, Pachman, Pachman, Petra Krol, Ravelli, Rider, Rider, Rider, Rider, Riley, Riley, Sally Smith, Salomonsson, Stringer, Symmons, Varsani, Wedderburn, Wedderburn, Wedderburn   +50 more
core   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination

Journal of Urological Surgery, 2020
Objective:To reveal the significance of core length in current primary transrectal ultrasound-guided prostate biopsy (TRUS-PB) in patients with normal digital rectal examination.Materials and Methods:Data of 3520 patients, who received TRUS-PB between ...
Mesut Altan, Burak Çıtamak, Emin Mammadov, Naime Meriç Konar, Bülent Akdoğan, Haluk Özen   +5 more
doaj   +1 more source