Results 141 to 150 of about 3,498,597 (337)
Advanced Science, EarlyView.Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
Understanding, Finding, and Conceptualizing Core Competence Depth: A Framework, Guide, and Generalization for Corporate Managers and Research Professionals: Working Paper Series--11-03 [PDF]
, 2011 In recent years, managerial interest in corporate core competencies as competitive tools has risen greatly. Corporate managers and professionals often have several questions regarding them. First, what are corporate core competencies?
Edgar, William B., Lockwood, Chris A.
core
Advanced Science, EarlyView.This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche +21 more
wiley +1 more source
中西医结合护理Objective To investigate the current condition and relationship of core competence and professional identity among critical care nurses in Guangyuan city, Sichuan Province, and provide reference for advanced skill training and management of critical ...
JIN Jinlong (靳金龙)
doaj +1 more source
Determining the Development Strategy and Suited Adoption Paths for the Core Competence of Shared Decision-Making Tasks through the SAA-NRM Approach. [PDF]
Int J Environ Res Public Health, 2022 Yu SF +6 more
europepmc +1 more source
Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation
Advanced Science, EarlyView.FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin +14 more
wiley +1 more source
ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication
Advanced Science, EarlyView.During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou +8 more
wiley +1 more source
Training of professional competence of nurses while studying core subjects [PDF]
, 2014 The problem of medical workers gets more actual nowadays that is determined by constant transformation of social experience, reconstruction of medical service sphere, the development of new technologies.
Дригало, А. В.
core
Nurr1 Orchestrates Claustrum Development and Functionality
Advanced Science, EarlyView.Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan +12 more
wiley +1 more source
Huli yanjiu, 2017 his article introduced the core competence of clinical nursing students and the general situation of problembased learning（PBL) teaching methods,and reviewed the impact of PBL teaching methods on the core competence of clinical nursing students,in order ...
朱瑞雪 +3 more
doaj