Results 51 to 60 of about 3,498,597 (337)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Cultivating key disciplinary competencies among university students against the background of China's new engineering education initiative.

PLoS ONE
The development of students' core disciplinary competencies is crucial to the quality of talent cultivation against the background of China's New Engineering Education initiative.
Liyuan Zheng, Di Ge
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Muatan Materi Sastra dalam Buku Teks Bahasa Indonesia Kelas VIII Serta Relevansinya dengan Kompetensi Inti dan Kompetensi Dasar [PDF]

, 2018
This study aims to describe (a) the content of material literary contained in Indonesian textbooks class VIII (b) the relevance of material literary contained in the Indonesian textbooks class VIII with the Core Competence of Curriculum 2013, and (c) the
, Drs. Zainal Arifin, M. Hum, Kinasih, Dewi   +1 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Core competencies of healthcare professionals in Oman: Research and evidence‐based practice needs attention

Nursing Open, 2023
Aim The aim of the study was to examine (1) the perceptions on core competencies of healthcare professionals working at clinical settings in Oman and (2) which demographic characteristics explain the overall core competency.
Fatma Al Jabri, Tarja Kvist, Hannele Turunen   +2 more
doaj   +1 more source

Community-based multicultural counselor preparation as a site of Praxis and social justice

, 2008
Recent calls in counseling psychology to embrace social justice work and mandates in the field to operationalize multicultural competencies have offered few mature examples of how this work actually looks.
Butler-Byrd, Nola, Nieto, Jesús, Senour, Maria Nieto   +2 more
core   +2 more sources

Double Screen Innovation: Building Sustainable Core Competence through Knowledge Management

Sustainability, 2019
How to exploit the precipitated internal and external knowledge to build dynamic capability in the era of big data remains a big challenge for innovation and business sustainability.
Ximing Yin, Jin Chen, Chuang Zhao
semanticscholar   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Pentingnya Pelatihan Kurikulum 2013 Bagi Guru [PDF]

, 2016
The purpose of this study is to express the importance of curriculum training for teachers before its implementation. Results of the study show, first, from the aspect of policy makers affirms that the naming of Curriculum 2013 curriculum ideas including
Sutjipto, S. (Sutjipto)
core   +2 more sources