Results 31 to 40 of about 69,694 (301)

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

The relationship between vocational core competencies and learning engagement of higher vocational students in Beijing: the mediating effect of professional commitment and moderating effect of gender

Humanities & Social Sciences Communications
This study delves into the relationship between vocational core competencies and learning competencies among 1002 higher vocational students, and the mediating role of professional commitment.
Xin Xie, Yaxin Xing, Chengxia Wang
doaj   +1 more source

Intercultural competencies required by organization development consultants [PDF]

, 2001
Plan BOrganization development (OD) is “a planned, system-wide change using behavioral science and humanistic values, principles, and practices to achieve greater organizational performance and effectiveness” (Ralphs, 1996).
Kothbauer, Teresa R.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developing New Competencies Among LIS Professionals: Challenges for Educators [PDF]

, 2008
This paper describes the development of library and information studies/science (LIS) into different phases during the last century. Academic programs and preparation of LIS professionals have witnessed a continuous change.
Sajjad, ur Rehman, Rehman, Sajjad ur
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Core competencies required of project managers

South African Journal of Business Management, 2000
Project management is internationally recognised as a management tool that is critical for success in the current work environment. In South Africa, initiatives are under way to produce internationally acceptable education and certification standards for
Michael Birkhead, Margaret Sutherland, Tudor Maxwell   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Factors influencing technical competencies in digital marketing of MSMEs in wholesale and retail sectors: the mediating role of core competencies

Business: Theory and Practice
While technology is essential for the survival of micro, small, and medium-sized businesses (MSMEs), their ability to use digital marketing effectively, especially in the wholesale and retail sectors, remains unclear.
Nathamon Buaprommee, Nachayapat Cuijten, Sureerut Inmor, Rungsan Suwannahong, Sukontip Wongpun   +4 more
doaj   +1 more source

Enhancing the Core Competencies of Auditors to Raise the Quality of Auditing : An Exploratory Study of the Opinions of a Sample of Academics and Professionals [PDF]

تنمیة الرافدین
In light of the rapid changes in the economic and financial environment, there is a growing need to enhance audit quality as a fundamental tool for ensuring transparency and accountability in financial reporting.
Arsalan Abdulkareem
doaj   +1 more source