Results 141 to 150 of about 558,921 (264)

chewBBACA 3: lowering the barrier for scalable and detailed whole- and core-genome multilocus sequence typing. [PDF]

Genome Med
Mamede R, Vila-Cerqueira P, Carriço JA, Ramirez M.   +3 more
europepmc   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Genetic Diversity and Spatial Distribution of <i>Yersinia pestis</i> by Core Genome-Based Multilocus Sequence Typing Analysis. [PDF]

Microorganisms
Appelt S, Rohleder AM, Schmidt K, Gatz J, Sedaghatjoo S, Scholz HC.   +5 more
europepmc   +1 more source

A core-genome multilocus sequence typing scheme for the detection of genetically related Streptococcus pyogenes clusters. [PDF]

J Clin Microbiol, 2023
Toorop MMA, Kraakman MEM, Hoogendijk IV, van Prehn J, Claas ECJ, Wessels E, Boers SA.   +6 more
europepmc   +1 more source

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Genomic epidemiology of antimicrobial resistance in Proteus mirabilis: core genome and plasmid-mediated drivers. [PDF]

BMC Microbiol
Zhang P, Cheng Z, Cao Y, Liu S, Zhao M.
europepmc   +1 more source

Core genome multilocus sequence typing of Clostridioides difficile to investigate transmission in the hospital setting. [PDF]

Eur J Clin Microbiol Infect Dis, 2023
Filippidis P, Senn L, Poncet F, Grandbastien B, Prod'hom G, Greub G, Guery B, Blanc DS.   +7 more
europepmc   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Development and validation of a core-genome multilocus sequence typing scheme for <i>Legionella longbeachae</i>. [PDF]

Microb Genom
Miller H, Harte D, Khokryakova I, Jordan R, Bradshaw A, Wang J, Winter D.   +6 more
europepmc   +1 more source