Results 161 to 170 of about 4,042,841 (387)

Core Genome Responses Involved in Acclimation to High Temperature

open access: yesPlant Physiology, 2007
AbstractPlants can acclimate rapidly to environmental conditions, including high temperatures. To identify molecular events important for acquired thermotolerance, we compared viability and transcript profiles of Arabidopsis thaliana treated to severe heat stress (45°C) without acclimation or following two different acclimation treatments.
Larkindale, Jane, Vierling, Elizabeth
openaire   +2 more sources

Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

open access: yesNature Communications, 2019
ATP can function as a biological hydrotrope, but its global effects on protein solubility have not yet been characterized. Here, the authors quantify the effect of ATP on the thermal stability and solubility of the cellular proteome, providing insights ...
Sindhuja Sridharan   +7 more
doaj   +1 more source

Solving Sequences of Generalized Least-Squares Problems on Multi-threaded Architectures

open access: yes, 2012
Generalized linear mixed-effects models in the context of genome-wide association studies (GWAS) represent a formidable computational challenge: the solution of millions of correlated generalized least-squares problems, and the processing of terabytes of
Aulchenko, Yurii   +2 more
core  

Whole-genome sequence diversity and association analysis of 198 soybean accessions in mini-core collections [PDF]

open access: gold, 2021
Hiromi Kajiya‐Kanegae   +12 more
openalex   +1 more source

Comprehensive Functional Analysis of the Enterococcus faecalis Core Genome Using an Ordered, Sequence-Defined Collection of Insertional Mutations in Strain OG1RF

open access: yesmSystems, 2018
The robust ability of Enterococcus faecalis to survive outside the host and to spread via oral-fecal transmission and its high degree of intrinsic and acquired antimicrobial resistance all complicate the treatment of hospital-acquired enterococcal ...
J. Dale   +11 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Air pollution modifies colonisation factors in beneficial symbiont Snodgrassella and disrupts the bumblebee gut microbiome

open access: yesnpj Biofilms and Microbiomes
Particulate air pollutants, a major air pollution component, are detrimental to human health and a significant risk to wildlife and ecosystems globally. Here we report the effects of particulate pollutant black carbon on the beneficial gut microbiome of ...
Hannah R. Sampson   +4 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Conversion of Methionine to Cysteine in Lactobacillus paracasei Depends on the Highly Mobile cysK-ctl-cysE Gene Cluster

open access: yesFrontiers in Microbiology, 2018
Milk and dairy products are rich in nutrients and are therefore habitats for various microbiomes. However, the composition of nutrients can be quite diverse, in particular among the sulfur containing amino acids.
Daniel Wüthrich   +5 more
doaj   +1 more source

Cryo-EM structures of herpes simplex virus type 1 portal vertex and packaged genome. [PDF]

open access: yes, 2019
Herpesviruses are enveloped viruses that are prevalent in the human population and are responsible for diverse pathologies, including cold sores, birth defects and cancers.
Bi, Guo-Qiang   +4 more
core  

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