Results 91 to 100 of about 10,123,200 (347)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Wave-Driven Mass Loss in the Last Year of Stellar Evolution: Setting the Stage for the Most Luminous Core-Collapse Supernovae

, 2012
During the late stages of stellar evolution in massive stars (C fusion and later), the fusion luminosity in the core of the star exceeds the star's Eddington luminosity.
Arnett, Bouret, Chomiuk, Christensen-Dalsgaard, Dessart, E. Quataert, Garcia Lopez, Goldreich, J. Shiode, Kiewe, Kippenhahn, Kumar, Meakin, Miller, Murphy, Ofek, Ofek, Paxton, Quimby, Rogers, Rogers, Smith, Smith, Smith, Smith, Smith, Unno, Woosley   +27 more
core   +1 more source

Effective control of the error in a direct measurement of core-loss power [PDF]

, 1995
Accuracy of a direct measurement of core-loss power is severely limited in many applications by the extra phase shift between the measured voltage and current.
Tan, F. Dong, Vollin, Jeff L., Ćuk, Slobodan   +2 more
core   +1 more source

Low-loss Multimoded Antiresonant Hollow Core Fiber

14th Pacific Rim Conference on Lasers and Electro-Optics (CLEO PR 2020), 2020
We report the first design for low-loss, multimoded antiresonant hollow-core fiber for applications requiring multiple modes. The designed fiber guides 6 - 9 spatially distinct core modes having confinement loss <0.001 - 0.01dB/m respectively.
Goel, Charu, Yoo, Seongwoo
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Simple ultraviolet-based soft-lithography process for fabrication of low-loss polymer polysiloxanes-based waveguides [PDF]

, 2011
A simple ultraviolet (UV)-based soft-lithography process is used for fabrication of polymer polysiloxanes (PSQ-L) waveguides. The imprint process is first done on the cladding PSQ-LL layer and is followed by a spin-coating step to fill the imprinted ...
Li, L, Morthier, Geert, Teng, J, Yan, H, Zhang, H, Zhao, M   +5 more
core   +2 more sources

Magnetization-Dependent Core-Loss Model in a Three-Phase Self-Excited Induction Generator

Energies, 2018
Steady-state, transient, as well as dynamic analyses of self-excited induction generators (SEIGs) are generally well-documented. However, in most of the documented studies, core losses have been neglected or inaccurately modeled.
Saleh H. Al-Senaidi, Abdulrahman I. Alolah, Majeed A. Alkanhal   +2 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Density functional theory calculations of the carbon ELNES of small diameter armchair and zigzag nanotubes: core-hole, curvature and momentum transfer orientation effects

, 2003
We perform density functional theory calculations on a series of armchair and zigzag nanotubes of diameters less than 1nm using the all-electron Full-Potential(-Linearised)-Augmented-Plane-Wave (FPLAPW) method.
A. Bougrine, A.J. Papworth, C. Hébert-Souche, D. Lamoen, D.M. Ceperley, D.N. Jayawardane, D.S. Bethune, G. Onida, H. Kataura, H.J. Liu, J. Bruley, J. Kürti, J. T. Titantah, J.P. Perdew, J.W. Mintmire, J.W. Mintmire, J.W. Mintmire, K. Jorissen, K. Suenaga, L. Duclaux, L.C. Venema, M. Baxendale, M. Endo, M. Inokuti, M. Knupfer, M. Knupfer, M. Machón, M. Menon, M. Menon, M. Menon, M. Nelhiebel, M. Taillefumier, M.A. Pimenta, O. Stéphan, P. Delaney, P. Hohenberg, P. Kim, P.E. Blöchl, P.J. Fallon, P.V. Huong, R. Saito, R.C. Haddon, R.C. Haddon, R.C. Haddon, R.J. Baierle, S. Iijima, S. Kazaoui, S. Reich, S. Suzuki, S. Suzuki, S.-H. Jhi, S.D. Berger, T. Dumitrică, T. Pichler, T.W. Ebbesen, V. Meunier, W. Kohn, W.K. Hsu, X. Blase, Y. Ma, Z.M. Li   +60 more
core   +1 more source

Core Structure and Electromagnetic Field Evaluation in WPT Systems for Charging Electric Vehicles

Energies, 2018
The electromagnetic field (EMF) in a wireless power transfer (WPT) system needs to couple inductively between the primary and the secondary coils through a large air gap, thus giving the system a loosely coupled characteristic.
Kamal Eldin Idris Elnail, Xueliang Huang, Chen Xiao, Linlin Tan, Xu Haozhe   +4 more
doaj   +1 more source