Results 61 to 70 of about 891,437 (305)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Designing power inductors: practical solutions [PDF]

, 2011
An overview of losses and thermal aspects if power inductors is given. Most of the time core losses are given only for sine square wave, but users use it in square waves. Also bulk currents affect losses in larger inductors.
Van den Bossche, Alex
core   +1 more source

Critical state solution of a cable made of curved thin superconducting tapes

, 2014
In this paper we develop a method based on the critical state for calculating the current and field distributions and the AC losses in a cable made of curved thin superconducting tapes.
Brambilla, Roberto, Grilli, Francesco
core   +1 more source

Core loss reduction in electrical steels through materials processing [PDF]

, 1999
Research has been conducted into the effects of laser scribing on the core losses of soft magnetic materials. Various types of lamination steels for use in electric motors and transformers were studied including iron based alloys containing carbon ...
Jiles, David, Jiles, David, Verbrugge, B.   +2 more
core   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Core Loss of MgZn Ferrite.

Journal of the Japan Society of Powder and Powder Metallurgy, 1999
The effects of substitution of Mn2O3 for Fe2O3 Or CuO for MgO in MgZn ferrite have been studied in order to achieve low core loss, focusing on the microstructure, the initial permeability and the resistivity of MnZn, MnMgZn, and MnMgCuZn ferrites.Initial permeability and resistivity of both MnMgZn and MnMgCuZn ferrites are higher than those of MgZn ...
Isao Kanada, Takuya Aoki, Taku Murase, Takeshi Nomura   +3 more
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Cool Core Clusters from Cosmological Simulations [PDF]

, 2015
We present results obtained from a set of cosmological hydrodynamic simulations of galaxy clusters, aimed at comparing predictions with observational data on the diversity between cool-core (CC) and non-cool-core (NCC) clusters.
Beck, A. M., Biffi, V., Borgani, S., Dolag, K., Granato, G. L., Murante, G., Planelles, S., Ragone-Figueroa, C., Rasia, E., Steinborn, L. K.   +9 more
core   +4 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source