Results 61 to 70 of about 2,316,046 (304)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Element 4 Letter to Chairs from UCOC Core General Education Assessment, 2023-2024
The Letter to Chairs from UCOC for Element 4 - Arts/Humanities as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Reduction in Core Loss in Amorphous Cut Cores with Air Gaps
In order to reduce core losses in amorphous cut cores with air gaps, the effects of ferrite plates attached to the cut surfaces of the cores were investigated. It was learned that the attachment of thin ferrite plates decreases the core loss remarkably in such cores.
Fukunaga, H. +4 more
openaire +2 more sources
Element 6 Core Assessment Plan Template Core General Education Assessment, 2018-2019
The Core Assessment Plant Template for Element 6 - Natural Science as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core
Element 4 List of Courses Core General Education Assessment, 2023-2024
The List of Courses for Element 4 - Arts/Humanities as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Using CORE to research outcome measurement [PDF]
Chris Leach and Mike Lucock have been involved with CORE from its beginning. Jointly responsible for the development of one of the first large databases of the use of CORE in routine clinical practice, they have published a number of key papers looking
Lucock, Mike, Leach, Chris
core +2 more sources
In this paper are presented some considerations about the performance of single wire earth return amorphous alloy core transformers in comparison with conventional silicon steel sheets cores transformers used in rural electric energy distribution network.
Benedito Antonio Luciano +4 more
doaj

