Results 61 to 70 of about 2,316,046 (304)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Element 4 Letter to Chairs from UCOC Core General Education Assessment, 2023-2024

open access: yes, 2023
The Letter to Chairs from UCOC for Element 4 - Arts/Humanities as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Reduction in Core Loss in Amorphous Cut Cores with Air Gaps

open access: yesIEEE Translation Journal on Magnetics in Japan, 1989
In order to reduce core losses in amorphous cut cores with air gaps, the effects of ferrite plates attached to the cut surfaces of the cores were investigated. It was learned that the attachment of thin ferrite plates decreases the core loss remarkably in such cores.
Fukunaga, H.   +4 more
openaire   +2 more sources

Element 6 Core Assessment Plan Template Core General Education Assessment, 2018-2019

open access: yes, 2019
The Core Assessment Plant Template for Element 6 - Natural Science as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core  

Element 4 List of Courses Core General Education Assessment, 2023-2024

open access: yes, 2023
The List of Courses for Element 4 - Arts/Humanities as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Using CORE to research outcome measurement [PDF]

open access: yes, 2007
Chris Leach and Mike Lucock have been involved with CORE from its beginning. Jointly responsible for the development of one of the first large databases of the use of CORE in routine clinical practice, they have published a number of key papers looking
Lucock, Mike, Leach, Chris
core   +2 more sources

Performance of single wire earth return transformers with amorphous alloy core in a rural electric energy distribution system

open access: yesMaterials Research, 2012
In this paper are presented some considerations about the performance of single wire earth return amorphous alloy core transformers in comparison with conventional silicon steel sheets cores transformers used in rural electric energy distribution network.
Benedito Antonio Luciano   +4 more
doaj  

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