Results 1 to 10 of about 8,173 (66)
Trudy Odesskogo Politehničeskogo Universiteta, 2019 The VVER reactor investigation is an important goal for Ukrainian nuclear energy. Different deterministic and stochastic codes are using for this purpose.
Володимир Іванович Гулік +3 more
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Frontiers in Immunology, 2022 The therapeutic targeting of the immune system, for example in vaccinology and cancer treatment, is a challenging task and the subject of active research.
Marcus Fabiano de Almeida Mendes +10 more
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Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 The haem enzyme indoleamine 2,3-dioxygenase 1 (IDO1) catalyses the rate-limiting step in the kynurenine pathway of tryptophan metabolism and plays an essential role in immunity, neuronal function, and ageing. Expression of IDO1 in cancer cells results in
Ute F. Röhrig +11 more
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Active-learning-based nonintrusive model order reduction
Data-Centric Engineering, 2023 Model order reduction (MOR) can provide low-dimensional numerical models for fast simulation. Unlike intrusive methods, nonintrusive methods are attractive because they can be applied even without access to full order models (FOMs).
Qinyu Zhuang +3 more
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Evidence for a trap-and-flip mechanism in a proton-dependent lipid transporter
Nature Communications, 2022 LtaA catalyzes glycolipid translocation by a ‘trap-and-flip’ mechanism, pointing to a shared mechanistic model among MFS lipid transporters. Asymmetric lateral openings allow access of the entire lipid substrate to the amphipathic central cavity.
Elisabeth Lambert +4 more
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Towards an efficient multiphysics model for nuclear reactor dynamics [PDF]
Nuclear Technology and Radiation Protection, 2015 Availability of fast computer resources nowadays has facilitated more in-depth modeling of complex engineering systems which involve strong multiphysics interactions. This multiphysics modeling is an important necessity in nuclear reactor safety
Obaidurrahman K., Gaikwad Avinash J.
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Scientific Reports, 2021 Myocardial infarction (MI) rapidly impairs cardiac contractile function and instigates maladaptive remodeling leading to heart failure. Patient-specific models are a maturing technology for developing and determining therapeutic modalities for MI that ...
Hao Liu +10 more
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Digital Core Modeling Based on Pretrained Generative Adversarial Neural Networks
Geofluids, 2022 Accurately establishing a 3D digital core model is of great significance in oil and gas production. The physical experiment method and numerical modeling method are common modeling methods.
Qing Zhang +5 more
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Application of SARAX code system on the calculation of complex unstructured geometry core
He jishu, 2023 BackgroundWith the increase of complexity of reactor core design, the core modeling and calculation have brought challenges.PurposeThis study aims to implement the accurate modeling and calculation of unstructured geometry core.MethodsBased on discrete ...
XIAO Bowen +5 more
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Transcriptomic study of Salmonella enterica subspecies enterica serovar Typhi biofilm
BMC Genomics, 2017 Background Typhoid fever is an acute systemic infection of humans caused by Salmonella enterica subspecies enterica serovar Typhi (S. Typhi). In chronic carriers, the bacteria survive the harsh environment of the gallbladder by producing biofilm.
Khee Chian Jason Chin +5 more
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