Results 61 to 70 of about 4,460,645 (227)
Journal of Infection and Public Health, 2019 Background: Hepatitis C virus (HCV) infection is an important cause of morbidity and mortality in patients with chronic kidney disease (CKD). The objective of this study was to predict the impact of EBR/GZR on the incidence of liver and kidney related ...
Chizoba Nwankwo +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The influence of regularization on the geomagnetic core field modeling
地球与行星物理论评Earth's magnetic field is generated through the dynamo action in the liquid outer core. Using observational data from geomagnetic satellites and observatories, we can construct geomagnetic models that describe spatial and temporal variations of the core ...
Juyuan Xu, Yufeng Lin, Keke Zhang
doaj +1 more source
Современная наука и инновации, 2022 He article describes the control system of technological parameters in the reactor core of the RBMK-1000. A scheme for the design of the graphite core of the reactor core is described.
A. L. Lyashenko
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Element 3 Assessment Report Template Core General Education Assessment, 2017-2018
, 2018 The Assessment Report Template for Element 3 - Interdisciplinary Global Studies as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core +2 more sources
The Core and Nucleolus in a Model of Information Transferal [PDF]
Journal of Applied Mathematics, 2012 Galdeano et al. introduced the so‐called information market game involving n identical firms acquiring a new technology owned by an innovator. For this specific cooperative game, the nucleolus is determined through a characterization of the symmetrical part of the core. The nonemptiness of the (symmetrical) core is shown to be equivalent to one of each,
Hou, Dongshuang, Driessen, Theo
openaire +3 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Element 2 Assessment Report Template Core General Education Assessment, 2019-2020
, 2020 The Assessment Report Template for Element 2 - Mathematics as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core +2 more sources
Defective ventral neurogenesis due to midfetal Chd8 mutation drives autistic-like behavior in mice
Nature CommunicationsAutism spectrum disorder (ASD) is a common neurodevelopmental condition characterized by behavioral abnormalities. Although mouse models have been widely adopted to recapitulate the pathology of ASD, the identification of specific neural abnormalities ...
Kenta Nitahara +10 more
doaj +1 more source