Results 111 to 120 of about 34,411 (209)

The evolving role of positron emission tomography in precision prostate cancer biopsy

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Prostate biopsy plays a pivotal role in the detection and characterization of prostate cancer. PSMA PET‐targeted biopsy represents a significant advancement in prostate cancer diagnostics, offering higher sensitivity, specificity and accuracy in detecting clinically significant lesions compared to traditional methods. PSMA PET, when combined with mpMRI,
Alessio Imperiale   +11 more
wiley   +1 more source

Open Questions in Surgery for Hepatoblastoma: A Joined SIOPEL‐IPSO Survey

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Introduction Surgery is pivotal in the management of hepatoblastoma (HB) although approaches and techniques may vary. The Liver Group of the International Society of Pediatric Oncology (SIOPEL) and the International Pediatric Surgical Oncology (IPSO) group collaborated to develop an online survey to investigate specific technical aspects and ...
Chiara Grimaldi   +9 more
wiley   +1 more source

Y12C mutation disrupts IMPDH cytoophidia and alters cancer metabolism

open access: yesThe FEBS Journal, EarlyView.
IMPDH, the rate‐limiting enzyme for de novo GTP synthesis, can form polymers and cytoophidia to enhance activity by reducing GTP inhibition. In this study, a Y12C mutation in IMPDH2 was introduced via ABEmax base‐editing in human cancer cell lines to disrupt IMPDH polymerisation.
Chia‐Chun Chang   +7 more
wiley   +1 more source

Data set for reporting paediatric renal tumours: recommendations from the international collaboration on cancer reporting (ICCR)

open access: yesHistopathology, EarlyView.
This is the first international data set, to our knowledge, produced by the International Collaboration on Cancer Reporting (ICCR) for the reporting of resection specimens of paediatric renal tumours with the aim of standardising pathology reports, facilitating international data comparisons and improving patient management globally.
E J Perlman   +12 more
wiley   +1 more source

Liquid Biopsy for Enhanced Specificity in Identifying Somatic Mutations in Aggressive Non‐Hodgkin Large B‐Cell Lymphoma: A Comparative Study of Cell‐Free DNA and Formalin‐Fixed Paraffin‐Embedded Tissue

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Formalin‐fixed paraffin‐embedded (FFPE) tumor biopsy is the current mainstay of genotyping, but is limited by its invasiveness and tumor heterogeneity. Plasma cell‐free DNA (cfDNA) constitutes a minimally invasive alternative that may better capture tumor‐derived profiles from circulating tumor DNA (ctDNA). This study compares the
Gayaththri Vimalathas   +7 more
wiley   +1 more source

Evaluation of directional vacuum-assisted breast biopsy: Report for the National Breast Cancer Centre final report, CHERE Project Report No 21 [PDF]

open access: yes
This project was commissioned by the National Breast Cancer Centre (NBCC). The objectives of the project, as set out in the call for expressions of interest, were to determine: 1.
Lorraine Ivancic, Marion Haas
core  

Assessment of Diagnostic Tools to Detect Acute Gas Bubble Disease in Atlantic Salmon (Salmo salar L.)

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Currently, diagnosis of gas bubble disease (GBD) in fish relies on visual observations of bubbles in various body parts and exophthalmus. These observations lack quantified information about gas bubble load, limiting their diagnostic value.
S. Stensby‐Skjærvik   +9 more
wiley   +1 more source

The impact of re‐characterizing metastatic pancreatic neuroendocrine tumors: A prospective study

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract The biology of metastatic pancreatic neuroendocrine tumors (panNET) may alter over time. It remains to be defined if, how, and when this patient group should be recommended to re‐evaluate the characteristics of their disease. This prospective single‐center, longitudinal cohort study at Uppsala University Hospital, Sweden (NCT03130205 ...
Kazhan Mollazadegan   +9 more
wiley   +1 more source

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