Results 141 to 150 of about 34,411 (209)

Clinicopathological and molecular characterization of KRAS wild‐type pancreatic ductal adenocarcinomas reveals precursor lesions with oncogenic mutations and fusions in RAS pathway genes

open access: yesThe Journal of Pathology, Volume 266, Issue 3, Page 337-351, July 2025.
Abstract Pancreatic ductal adenocarcinomas (PDACs) with wild‐type KRAS constitute a small fraction of PDACs, and these tumors were recently shown to harbor frequent actionable oncogenic mutations and fusions. However, the clinicopathological features of KRAS wild‐type PDAC have not been well studied.
Kazuhiro Toriyama   +14 more
wiley   +1 more source

Can Artificial Intelligence Software be Utilised for Thyroid Multi‐Disciplinary Team Outcomes?

open access: yesClinical Otolaryngology, Volume 50, Issue 4, Page 769-774, July 2025.
ABSTRACT Objectives ChatGPT is one of the most publicly available artificial intelligence (AI) softwares. Ear, nose and throat (ENT) services are often stretched due to the increasing incidence of thyroid malignancies. This study aims to investigate whether there is a role for AI software in providing accurate thyroid multidisciplinary team (MDT ...
Amir Habeeb   +5 more
wiley   +1 more source

Ultrasound fundamentals and their clinical implications for interventional cytopathologists

open access: yesCytopathology, Volume 36, Issue 4, Page 356-374, July 2025.
Interventional cytopathologists need to know about ultrasound physics and instrumentation to produce an image that faithfully recreates the lesion discovered by the sonographer and diagnosed by the radiologist. A deep quantitative understanding of physics is not required.
David Lieu
wiley   +1 more source

Retrospective study: Laser excision versus combined laser, cryosurgery and intralesional 5‐fluorouracil in the treatment of equine sarcoids

open access: yesEquine Veterinary Education, Volume 37, Issue 7, Page 353-362, July 2025.
Summary Background Laser excision is used routinely in the treatment of sarcoids but may be ineffective in cases where complete excision cannot be achieved. A multimodal approach is warranted in these cases. 5‐FU may improve the lethal effect of cryosurgery as an adjunct to laser excision.
Katie S. Offer, David G. M. Sutton
wiley   +1 more source

A review of artificial intelligence in brachytherapy

open access: yesJournal of Applied Clinical Medical Physics, Volume 26, Issue 6, June 2025.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen   +4 more
wiley   +1 more source

Biohybrid Vascular Graft Made of Textile‐Reinforced Elastin‐Like Recombinamers and Its Preservation via Drying Processes

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 15, 10 June, 2025.
Clinical translation of biohybrid medical implants requires the previous implementation of drying schemes that can facilitate their sterilization and storage. This study addresses that critical aspect and elucidates the impact of drying on biohybrid vascular grafts, highlighting the need for implant‐specific drying strategies to ensure safety ...
Dominic Pascal Andre   +5 more
wiley   +1 more source

Multiplexed Bio‐detection on an Interferometric Optical Waveguide Assembly

open access: yesAdvanced Materials Interfaces, Volume 12, Issue 11, June 9, 2025.
Multiplexed remote bio‐detection is demonstrated through an image conduit composed of 3012 individual cores and coated with interferometric layers. The proof of concept of biodetection is performed through the kinetic monitoring of two complementary DNA strands hybridization paving the way for applications in multiplex in situ biosensing, and ...
Oleksii Bratash   +6 more
wiley   +1 more source

Identification of Tumor‐Specific Surface Proteins Enables Quantification of Extracellular Vesicle Subtypes for Early Detection of Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, Volume 12, Issue 21, June 5, 2025.
Pancreatic ductal adenocarcinoma (PDAC) extracellular vesicle (EV) surface protein assay operates via a two‐step workflow – Step 1: Click chemistry‐mediated enrichment of PDAC EVs by EV Click Beads, in the presence of one of the three trans‐cyclooctene‐grafted PDAC EV‐specific antibodies; Step 2: Quantification of the enriched PDAC EVs by reverse ...
Chen Zhao   +27 more
wiley   +1 more source

SSRP1/SLC3A2 Axis in Arginine Transport: A New Target for Overcoming Immune Evasion and Tumor Progression in Peripheral T‐Cell Lymphoma

open access: yesAdvanced Science, Volume 12, Issue 21, June 5, 2025.
Enhanced arginine uptake is a critical feature of metabolic reprogramming in PTCL, characterized by elevated expression of the arginine transporter SLC3A2. SLC3A2‐mediated arginine uptake facilitates PTCL proliferation and survival by enhancing OXPHOS metabolism and inducing immune evasion.
Yimin Ren   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy