Results 81 to 90 of about 80,621 (304)

ZFPL1 Promotes Colorectal Cancer Progression by Stabilizing ASS1 to Drive the Urea Cycle and M2 Macrophage‐Mediated Metastatic Colonization

Advanced Science, EarlyView.
ScRNA‐seq reveals ZFPL1‐specific enrichment in malignant CRC cells. Mechanistically, ZFPL1 stabilizes ASS1 by blocking K57 ubiquitination, activating urea cycle metabolism to drive progression. ZFPL1 inhibition reprograms the TME by suppressing M2 macrophages polarization and promotion M1 macrophages, thereby inhibiting CRC liver metastasis ...
Xiangjun Qian, Chenxi Xie, Beilin Zhang, Hengsong Cao, Zhengqing Lu, Li Liu, Shipeng Dai, Xiaoqian Wang, Xiaokai Zhang, Feng Han, Yanyan Liu, Haibo Yu, Weiwei Tang, Jinxue Zhou, Xiaopei Hao   +14 more
wiley   +1 more source

Video-Assisted Thoracic Surgery Core Needle Biopsy for Pulmonary Nodules in Patients with Impaired Lung Function: Is It Feasible and Safe?

Journal of Chest Surgery, 2023
Background: The number of patients with incidentally identified pulmonary nodules is increasing. This study attempted to confirm the usefulness and safety of video-assisted thoracic surgery (VATS) core needle biopsy of pulmonary nodules. Methods: Data
Yong-Seong Lee, Jong Duk Kim, Hyun-Oh Park, Chung-Eun Lee, In-Seok Jang, Jun-Young Choi   +5 more
doaj   +1 more source

Risk of complications after core needle biopsy in pheochromocytoma/paraganglioma [PDF]

, 2023
Liang Zhang, Tobias Åkerström, Kazhan Mollazadegan, Felix Beuschlein, Karel Pacák, Britt Skogseid, Joakim Crona   +6 more
openalex   +1 more source

Pregnancy-associated breast cancer - Special features in diagnosis and treatment [PDF]

, 2006
For obvious psychological reasons it is difficult to associate pregnancy - a life-giving period of our existence with life-threatening malignancies. Symptoms pointing to malignancy are often ignored by both patients and physicians, and this, together ...
Bauerfeind, I., Dian, D., Friese, K., Gerber, B., Janni, W., Krause, A., Rack, B., Sommer, H.   +7 more
core   +1 more source

Muscle Organoids Reveal Exercise‐Like Contractions Rapidly Promote Muscle Health Via Lamtor1's Signaling to Both AMPK and mTOR

Advanced Science, EarlyView.
This study develops a novel 3D human skeletal muscle organoid platform to study the immediate molecular effects of exercise‐like contractions. The model uncovers rapid proteomic and transcriptomic responses, resolving a fundamental paradox by demonstrating how exercise‐induced Lamtor1 coordinately activates both AMPK and mTORC1. Lamtor1 is a compelling
Ziyue Yao, Zongmin Jiang, Xupeng Liu, Liping Zhang, Siyu Guo, Yu Chen, Lanfang Luo, Shilin Ma, Peng Wang, Ng Shyh‐Chang   +9 more
wiley   +1 more source

Computed tomography–guided percutaneous transthoracic core needle biopsy for the diagnosis of mediastinal masses

The Journal of Association of Chest Physicians
Mediastinal masses encompass a wide spectrum of diseases; therefore, histopathological diagnosis is crucial for adequate surgical or medical treatments.
Sukanta Kodali, Sourindra Nath Banerjee, Jaydip Deb, Pulak Kumar Jana   +3 more
doaj   +1 more source

Galectin-3 performance in histologic and cytologic assessment of thyroid nodules. A systematic review and meta-analysis [PDF]

, 2017
The literature on Galectin-3 (Gal-3) was systematically reviewed to achieve more robust information on its histologic reliability in identifying thyroid cancers and on the concordance between Gal-3 test in histologic and cytologic samples.
Crescenzi, Anna, Giovanella, Luca, Romanelli, Francesco, Trimboli, Pierpaolo, Virili, Camilla   +4 more
core   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

Advanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan, Mengyao Zhang, Haiyue Guo, Yan Xu, Chenjie Xu, Fan Hu, Yinbing Pan, Xian Wang, Wentao Liu, Chun‐Yi Jiang   +9 more
wiley   +1 more source

Ultrasound-Guided Core Needle Biopsy for Salivary Gland Lesions

Gomal Journal of Medical Sciences, 2004
Background: A salivary gland swelling may result from various causes and create a diagnostic challenge. This study was conducted to evaluate the usefulness of ultrasound-guided core needle biopsy as a diagnostic modality.
Syed Qaiser Husain Naqvi, Shamsuddin Shaikh, Syed Qarib Abbas Shah, Jan Muhammad Memon, Anwar Ali Akhund, Tabinda Taqi   +5 more
doaj  

Metastasis to parotid gland from non Head and Neck tumors [PDF]

, 2018
Most primary tumors spreading metastasis to the parotid gland are usually located in the head and neck region, nonetheless, rarely, parotid gland can also be the target of metastatic localization site of distant primary tumors.
Andrea, Ciorba, Bianchini, Chiara, Borsetto, Daniele, Cazzador, Diego, Enzo, Emanuelli, Francesco, Stomeo, Fusetti, Stefano, Marino, Filippo, Sarcognato, Samantha, Stefano, Pelucchi   +9 more
core