Results 31 to 40 of about 645,932 (259)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Frontiers in PhysiologyBackgroundPostural control integrates core stability, coordination, and balance shaped by specific training. Sprinting emphasizes stretch–shortening-cycle power and trunk extensor use, whereas Chinese martial arts stress multi-planar core-hip control ...
Huanhuan Zhu +5 more
doaj +1 more source
Diagnostics, 2021 The abdominal drawing-in maneuver (ADIM) is a clinical tool used for identifying preferential activity of deep abdominal muscles. However, concurrent validity and reproducibility of palpation during the ADIM has not been formally investigated.
Irene Valentín-Mazarracin +7 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Sex-specific DNA-replication in the early mammalian embryo
Nature CommunicationsThe timing of DNA replication in mammals is crucial for minimizing errors and influenced by genome usage and chromatin states. Replication timing in the newly formed mammalian embryo remains poorly understood.
Jason Alexander Halliwell +5 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Investigating the Effects of Adding Kinesio Taping to Diaphragm Strengthening Exercises on Pain, Function, Core Muscle Endurance, Agility, and Balance in Female Athletes with Chronic Non-specific Low Back Pain: A Randomized Clinical Trial Study Protocol [PDF]
Journal of Rehabilitation Sciences and ResearchBackground: Chronic non-specific low back pain (NS-LBP) is a prevalent musculoskeletal condition affecting athletes. While core muscle strengthening is effective in managing NS-LBP, the role of the diaphragm in spinal stability is often overlooked ...
Sara Jafarpour +3 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The Effects of Core Stabilization Trunk Muscle Fatigue on Lower Limb Stiffness of Basketball Players
Sports, 2023 Core stability is the ability to control the position and motion of the trunk over the pelvis and legs to allow the optimum production and transfer of force to the terminal segment in sporting activities.
Mehdi Khaleghi Tazji +6 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source