Results 111 to 120 of about 3,973,532 (276)

Gastrointestinal Symptoms Predictors of Health-Related Quality of Life in Pediatric Patients with Functional Gastrointestinal Disorders

, 2017
OBJECTIVES: To investigate the patient-reported multidimensional gastrointestinal symptoms predictors of generic health-related quality of life (HRQOL) in pediatric patients with functional gastrointestinal disorders (FGIDs).
Self, Mariella M., Shulman, Robert J., Varni, James W., Saeed, Shehzad Ahmed, Nurko, Samuel, Pediatric Quality of Life Inventory™ Gastrointestinal Symptoms Module Testing Study Consortium, Bendo, Cristiane B, Dark, Chelsea Vaughan, Patel, Ashish S., Saps, Miguel, Pohl, John F.   +10 more
core   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Early language skills and later internalizing and externalizing behaviours: associations through core and pragmatic language

Child and Adolescent Psychiatry and Mental Health
Background Language skills have been associated with both internalizing (anxiety, depression, somatization) and externalizing (conduct problems, hyperactivity, aggression) behaviours.
Anna-Elisabeth Baumann, Lorraine D. Reggin, Karolina Wieczorek, Suzanne Tough, Susan A. Graham   +4 more
doaj   +1 more source

“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez, Carmen Espejo, Georgina Arrambide, Mireia Castillo, Marta Rodriguez, Helena Ariño, Iker Elosua, Carmen Tur, Angela Vidal‐Jordana, Andreu Vilaseca, Joaquín Castilló, Ingrid Galán, Luciana Midaglia, Carlos Nos, Breogan Rodríguez‐Acevedo, Ana Zabalza, Luca Bollo, Agustín Pappolla, René Carvajal, Neus Mongay‐Ochoa, Jordi Rio, Jaume Sastre‐Garriga, Manuel Comabella, Gesualdina Busiello, Sofia Sceppacuercia, Àlex Rovira, Xavier Montalban, Mar Tintoré, Cristina Auger, Álvaro Cobo‐Calvo   +29 more
wiley   +1 more source

Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl, Marika C. Möller, Lindsay Wilson, Anne Vik, Toril Skandsen, Jonas Stenberg, CENTER‐TBI participants and investigators   +6 more
wiley   +1 more source

Acupoint-symptom quantitative analysis of acupuncture for alleviating gastrointestinal symptoms after chemotherapy for cancer

World Journal of Acupuncture - Moxibustion
Objective: To define the core acupoints for improving gastrointestinal symptoms after chemotherapy, clarify their association with primary indications, and provide a scientific basis for optimizing clinical acupoint selection and constructing evidence ...
Shuai-yan WANG, Si-yu ZHUANG, Meng-zhe ZHANG, Xin LIU, Yi-ming LI, Guan-hu YANG, Tian-cheng XU   +6 more
doaj   +1 more source

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui, Jiayang Zhan, Wei Li, Tao Jin, Dan He, Daishi Tian, Zhijun Li, Jing Lin, Yue Li, Hongyu Zhou, Bitao Bu   +10 more
wiley   +1 more source

Symptom clusters and networks analysis in acute-phase stroke patients: a cross-sectional study

Scientific Reports
The symptoms of stroke jeopardize patients’ health and increase the burden on society and caregivers. Although the traditional symptom cluster research paradigm can enhance management efficiency, it fails to provide targets for intervention, thereby ...
Siyu Zhou, Yuan Zhang, Huijuan He, Xiangrong Wang, Mengying Li, Na Zhang, Jiali Song   +6 more
doaj   +1 more source

Clinical phenotypes of anorexia nervosa: mathematical models based on latent class analysis of psychopathological symptoms

Consortium Psychiatricum
BACKGROUND: Anorexia nervosa (AN) is characterized by heterogeneous clinical manifestations, which complicates diagnosis and treatment. It is important to define the clinical variants and therapeutic targets for AN.
Olga A. Karpenko, Timur S. Syunyakov, Alexander B. Berdalin, Anastasia V. Evlampieva, Olga V. Andrianova, Laura E. Gilmutdinova, Alla V. Novichkova, Andrey K. Aleksanian, Julia A. Nikolkina, Evgeniya V. Mazurova, Aleksey A. Shafarenko, Lyudmila S. Satyanova   +11 more
doaj   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source