Results 81 to 90 of about 3,973,532 (276)

Study on the network of postoperative symptoms and its influencing factors in esophageal cancer patients

Frontiers in Oncology
Esophageal cancer(EC) is a common and highly invasive malignant tumor of the digestive tract, for which surgery remains a key treatment modality. Postoperative patients frequently experience multiple coexisting physical and psychological symptoms.
Jing Zhao, Yina Liu, Bingbing Xiao, Tingting Tan, Yiting Yin, Yang Hu, Li Li   +6 more
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Network analysis of symptom cluster and core symptoms in peritoneal dialysis patients

Huli yanjiu
ObjectiveTo investigate the incidence and severity of symptoms in peritoneal dialysis patients,so as to identify symptom clusters.To construct concurrent symptom networks,to explore core symptoms,so as to provide references for clinical medical staff to ...
ZHANG Li, HAN Lingyu, WANG Shuohan, YANG Qi, ZHAO Xinyi, CUI Xin, DONG Mei   +6 more
doaj  

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Simultaneous Symptom Network Analysis of Heart Failure Patients: A Cross-Sectional Study

Risk Management and Healthcare Policy
Rui Wu,1,2 Lu Chen,3 Yingjie Li,3 Huiwen Wang,3 Mengdie Liu,3 Yingxia Yao,3 Huiyan Chen,3 Dan Xiao4 1Department of Cardiology, The Second Affiliated Hospital of Jiangxi Medical College, Nanchang University, Nanchang, People’s Republic of China; 2School ...
Wu R, Chen L, Li Y, Wang H, Liu M, Yao Y, Chen H, Xiao D   +7 more
doaj  

Network analysis of core symptom changes in hepatocellular carcinoma survivors after transarterial chemoembolization: A longitudinal study

Frontiers in Oncology
ObjectiveThe aims of this study were to explore the longitudinal trajectories of core symptoms in survivors with hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE) and to analyze their associations with health-related quality of ...
Suping Wang, Xiuyan Wang, Ni Jiang, Yongpei Hu, Lirong Guo, Long Zhang, Yanzhe Liu, Simin Kong, Ying Zhang, Ying Zhang   +9 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

A network analysis of core symptoms in menopausal syndrome

Journal of Psychosomatic Obstetrics and Gynecology
Background Menopausal symptoms are common during the menopausal transition and can substantially affect women’s physical and psychological health. These symptoms often co-occur and interact, but their complex interrelationships and the symptoms that play
Huan Wu, Danfeng Gao, Liwen Song
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Core preoperative symptoms and patients’ symptom experiences in oral cancer: a mixed-methods study

Supportive Care in Cancer
Patients with oral cancer frequently experience a substantial symptom burden, especially during the preoperative phase, which is typically marked by increased anxiety, pain, and functional impairments. This study aimed to construct contemporaneous symptom networks and investigate symptom experiences of patients with preoperative oral cancer in China ...
Yu Zhang, Jingya Yu, Tingting Liu, Lixia Kuang, Xiaoqin Bi   +4 more
openaire   +2 more sources