Results 81 to 90 of about 401 (227)

Equine Hoof Progenitor Cells Display Increased Mitochondrial Metabolism and Adaptive Potential to a Highly Pro-Inflammatory Microenvironment. [PDF]

Int J Mol Sci, 2023
Pielok A, Kępska M, Steczkiewicz Z, Grobosz S, Bourebaba L, Marycz K.   +5 more
europepmc   +1 more source

Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma

Allergy, EarlyView.
Staphylococcus aureus, commonly colonising CTCL patients, augments skin barrier dysfunction. Staphylococcal enterotoxins induce T‐cell release of barrier‐repressing cytokines (IL‐4, IL‐13, IL‐22, OSM). Cytokine signalling drives JAK‐dependent downregulation of filaggrin and loricrin in keratinocytes. Antibiotic‐mediated eradication of S. aureus induces
Maria Gluud, Emil M. Pallesen, Ziao Zeng, Martin R. J. Namini, Chella Krishna Vadivel, Lise Mette Rahbek Gjerdrum, Lang Yan, Sana Ahmad, Lise M. Lindahl, Michael Bzorek, Maria R. Kamstrup, Saptaswa Dey, Sisse Rye Ostrowski, Erik Sørensen, Pia Rantakari, Charlotte Menne Bonefeld, Carsten Geisler, Anders Woetmann, Riitta Lahesmaa, Lars Iversen, Peter Wolf, Thomas Litman, Terkild B. Buus, Niels Ødum   +23 more
wiley   +1 more source

Divergent Paths: A Comprehensive Review of Mechanisms and Clinical Implications in Atopic Dermatitis and Psoriasis

Allergy, EarlyView.
ABSTRACT Atopic dermatitis and psoriasis are two common cutaneous chronic inflammatory diseases. Although they share similar immunological mechanisms, their clinical implications in the patient are different. This review compares both diseases from different points of view such as genetics, natural history, triggers of disease, and skin barrier defects
Tali Czarnowicki, Kazunari Sugita, Zenas Yiu, Sandra Díez‐Ribas, Irene Garcia‐Jimenez, Emma Guttman‐Yassky, Luis F. Santamaria‐Babí   +6 more
wiley   +1 more source

Nano-adjuvanted dry powder vaccine for the mucosal immunization against airways pathogens. [PDF]

Front Vet Sci, 2023
Canelli E, Ferrari L, Borghetti P, Candela F, Abiakam NS, Bianchera A, Buttini F, Magi GE, Sonvico F, Martelli P, Bettini R.   +10 more
europepmc   +1 more source

Rapid Human Skin Barrier Disruption by Sodium Dodecyl Sulfate and Associated Molecular Mechanisms

Allergy, EarlyView.
Short‐term exposure to SDS rapidly disrupts human skin barrier integrity within minutes, as detected by real‐time electrical impedance spectroscopy. SDS‐induced barrier dysfunction is driven by oxidative stress, leading to suppression of immune/barrier mediators and activation of stress, lipid remodeling, and epidermal differentiation pathways ...
Manru Li, Huseyn Babayev, Paolo D'Avino, Can Zeyneloğlu, Ceren Bicer, Duygu Yazici, Yagiz Pat, Per Svedenhag, Nicolas Gaudenzio, Cezmi A. Akdis, Yasutaka Mitamura   +10 more
wiley   +1 more source

Sentinel Lymph Node Biopsy in Clinically Node‐Negative Merkel Cell Carcinoma: An Update of the Westmead Hospital Experience

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine malignancy with a high risk of nodal metastasis. Sentinel lymph node biopsy (SLNB) is used to stage clinically node‐negative disease and to guide adjuvant therapy decisions.
Julie Ahn, Julie R. Howle, Michael J. Veness   +2 more
wiley   +1 more source

A case of canine urothelial carcinoma of the urinary bladder with skull and skeletal metastases

Australian Veterinary Journal, EarlyView.
Canine urinary bladder neoplasia is uncommon, representing less than 1% of canine neoplasms. Amongst cases of urinary bladder neoplasia in dogs, primary urothelial carcinoma is the most frequent. Urothelial carcinomas are malignant invasive tumours which tend to be slow growing and metastasise late.
A Teh, T Sima, E Shinozaki, R Malik
wiley   +1 more source

Equine Hoof Stem Progenitor Cells (HPC) CD29 + /Nestin + /K15 + - a Novel Dermal/epidermal Stem Cell Population With a Potential Critical Role for Laminitis Treatment. [PDF]

Stem Cell Rev Rep, 2021
Marycz K, Pielok A, Kornicka-Garbowska K.   +2 more
europepmc   +1 more source

Shared and specific molecular mechanisms of proteasome inhibitors in chemotherapy‐induced peripheral neurotoxicity

British Journal of Pharmacology, EarlyView.
This study compares the molecular mechanisms of chemotherapy‐related peripheral neurotoxicity of two proteasome inhibitors, bortezomib and carfilzomib, using a multidisciplinary approach to reveal that, alongside shared effects on mitochondria structure and function, the more neurotoxic drug BTZ has specific effects on microtubules and mitochondrial ...
Federico Iseppon, Alessio Malacrida, Alessia Chiorazzi, Annalisa Canta, Paola Alberti, Valentina Alda Carozzi, Eleonora Pozzi, Virginia Rodriguez‐Menendez, Laura Cherchi, Valentina Fabbro, Lisa Pagani, Elisa Tonelli, Laura Tapella, Andrea Mattarei, Sara Palermo, Daniele Cartelli, Mario Mauri, Noemi Scimia, Serena Stanga, Dmitry Lim, Carla Distasi, Marta Delconti, Clizia Chinello, Patricia Morcillo, Maria Elena Pero, Francesca Bartolini, Guido Cavaletti, Cristina Meregalli   +27 more
wiley   +1 more source

Patch Test Results With Additions to the European Baseline Series, 2021/22—Joint European Results of the ESSCAA and the EBSB Working Groups of the ESCD, and the GEIDACC

Contact Dermatitis, EarlyView.
ABSTRACT Background Allergens are periodically added to the European Baseline Series (EBS) to audit their value in consecutive patch testing. Objectives To present results of audit allergens tested in consecutive patients in 54 departments in 13 European countries during 2021 and 2022.
Wolfgang Uter, Stephen Mark Wilkinson, Andrea Bauer, Leopoldo Borrego, Richard Brans, Timo Buhl, Heinrich Dickel, Rosella Gallo, Ana Giménez Arnau, Margarida Gonçalo, Dimitra Koumaki, Alexander A. Navarini, Cataldo Patruno, Györgyi Pónyai, Thomas Rustemeyer, Radoslaw Spiewak, Luca Stingeni, Skaidra Valiukevičienė, Marie‐L. A. Schuttelaar, Olivier Aerts, the ESSCA, EBS, ESCD working groups, the GEIDAC, Birger Kränke, Ella Dendooven, Dagmar Simon, Philip Spring, Ulrike Beiteke, Cecilia Dietrich, Sibylle Schliemann, Detlef Becker, Swen Malte John, Nicola Wagner, Elke Weisshaar, Stamatis Gregoriou, Maddalena Napolitano, Philippa Cousen, Graham A. Johnston, Juan Francisco Silvestre Salvador, José Manuel Carrascosa Carrillo, Mónica Munera Campos, Esther Serra Baldrich, Gemma Melé‐Ninot, Cristina Barrabés Torrella, David Pesqué, Ana María Giménez Arnau, María Antonia Pastor Nieto, Francisco Navarro Triviño, Leopoldo Borrego, Inmaculada Ruiz Gonzales, Enrique Gómez de la Fuente, Susana Córdoba Guijarro, Francisco Javier Ortiz de Frutos, Fátima Tous Romero, Tatiana Sanz Sánchez, Pablo Chicharro Manso, Marta Andreu Barasoain, Marta Elosua González, Araceli Sánchez Gilo, Paloma Sánchez‐Pedreño Guillén, Pedro Mercader‐García, Carmen Paredes Suárez, María Elena Gatica Ortega, José Juan Pereyra Rodríguez, Javier Miquel Miquel, Mercedes Rodríguez Serna, Violeta Zaragoza Ninet, Ricardo González Pérez   +68 more
wiley   +1 more source