Results 61 to 70 of about 401 (227)

Assessment of thermal safety margins for the IVR-ERVC strategy of the i-SMR using the CINEMA code

Nuclear Engineering and Technology
In-vessel corium retention with external reactor vessel cooling (IVR-ERVC) is a key severe accident mitigation strategy to prevent lower-head failure and retain fission products inside the reactor vessel. This study assesses the applicability of IVR-ERVC
Dong-Hun Shin, Sang Ho Kim, Donggun Son, Yonadan Choi, Young Hee Kim, Hyoung Suk Yu, Yong Hoon Jeong   +6 more
doaj   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Transient Investigation of Conceptual Twin Crucible Type Core Catcher Design with Embedded Cooling Tube Using GOTHIC 3D Model

Yuanzineng kexue jishu
In case of a severe accident, the lower head of the reactor pressure vessel will be melted when the corium cannot be effectively cooled after melting. Under the EVR (ex-vessel corium retention) strategy, the molten corium will be released into the core ...
LIU Zhuo1, 2, , YUAN Yidan1, 2, JIA Ningxi1, 2, JIN Yu1, 2
doaj   +1 more source

Exploring the Chemical Complexity and Toxicological Behaviour of Semi‐permanent Make‐Up Pigments: A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye, M. B. Komane, A. P. Manyisane, R. Manganyi   +3 more
wiley   +1 more source

Oral PHGG ameliorates atopic dermatitis‐like dermatitis with concurrent modulation of colonic IgA and cecal microbiota: implications for the gut–skin axis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza, Hyeonjun Yu, Jonghyun Jeong, Jung Cheul Shin, Woo Jung Kim, Sung‐Kwon Moon, Hoon Kim   +6 more
wiley   +1 more source

Classification of High‐ and Low‐Risk Patients With Dermal Leiomyosarcoma: An Exploratory Nationwide Cohort Study

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Risk factors for dermal leiomyosarcoma (dLMS) metastasis remain poorly defined because methodological constraints, small sample sizes, and short follow‐up have limited previous studies. Objectives To investigate risk factors for metastasis and local recurrence, and to propose a high‐ and low‐risk classification for dLMS. Methods All
Kiya Abebe, Anders Munch, Anne Lene Wagenblast, Grethe Schmidt, David Hebbelstrup Jensen, Michael M. Petersen, Anand C. Loya, Søren Daugaard, Thomas Mentzel, Mikkel Herly, Peter Vester‐Glowinski, Mathias Ørholt   +11 more
wiley   +1 more source

Molten Pool Stratification Morphology Study with Thermodynamic Calculation

Yuanzineng kexue jishu
The molten pool stratification morphology within lower head under various operating conditions is crucial for optimizing the IVR (in-vessel retention) strategy and enhancing safety measures during severe accidents. In recent decades, many prototype tests
CHEN Erhui1, ZHANG Li1, LI Nan1, YUAN Yidan1, , DING Yeqing2, LU Xiaogang2
doaj   +1 more source

Clinical Efficacy and Safety of Topical Roflumilast in Psoriasis: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak, Ahmed Javed, Ummi Aiman Rahman, Rumaisa Riaz, Zeeshan Imtiaz, Hassan A. Mirza, Farman U. Khan, Muhid Khattak, Fatima Javid, Abdul Moiz Khan, Adeline L. Roy, Bibek Shrestha   +11 more
wiley   +1 more source

Experimental Study on Contact Melting of a Metal Plate by a Crusted Corium Considering Intermetallic Interactions

Applied Sciences
Under severe reactor accident conditions, the solidified crust of a relocated corium pool may undergo contact melting of internal metallic structures. This process, significantly influenced by complex intermetallic interactions, deviates markedly from ...
Junjie Ma, Yuqing Chen, Wenzhen Chen, Hongguang Xiao   +3 more
doaj   +1 more source

Characteristics of Sensitive Scalp in French Women and Comparison With Scalp Dermatoses

JEADV Clinical Practice, EarlyView.
ABSTRACT Background A sensitive scalp is a particular location of sensitive skin, characterised by the occurrence of unpleasant sensations which cannot be explained by a skin disease. It is a common syndrome that could affect 30%–50% of women. Clinical data are scarce, and the impact on the quality of life poorly described.
Ficheux Anne‐Sophie, Melessike Kristel, Misery Laurent, Brenaut Emilie   +3 more
wiley   +1 more source