Results 91 to 100 of about 1,298,398 (358)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Effect of Prices, Traits and Market Structure on Corn Seeding Density [PDF]

open access: yes
Recent agronomic research finds that economically optimal seeding densities have likely increased for many Midwestern corn farmers as a result of genetic improvements including new GM traits such as Bt corn and herbicide tolerance.
Lauer, Joseph G.   +3 more
core   +1 more source

Short Season Corn Silage Variety Trial [PDF]

open access: yes, 2012
In 2012, the University of Vermont Extension Crops and Soils Team evaluated yield and quality of short season corn silage varieties at Borderview Research Farm in Alburgh, VT.
Burke, Conner   +5 more
core   +2 more sources

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Study on the effect of microbial agent M44 on straw decay promoting in cold soils

open access: yesScientific Reports
Compound microbial agents are an important means to optimize soil quality and maintain soil microbial activity. When supplemented with microbial agents, straw returned to a field shows improved degradation efficiency and hence better nutrient release ...
Lijie Wang   +7 more
doaj   +1 more source

Nanobody and CuS Nanoflower-Au-Based Lateral Flow Immunoassay Strip to Enhance the Detection of Aflatoxin B1

open access: yesFoods
In the realm of analysis, the lateral flow immunoassay (LFIA) is frequently utilized due to its capability to be fast and immediate. However, the biggest challenge of the LFIA is its low detection sensitivity and tolerance to matrix interference, making ...
Yiming Zhao   +4 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Integrated transcriptomic and metabolomic analyses reveal optimized cultivation strategies for purple potatoes (Solanum tuberosum L.)

open access: yesFrontiers in Plant Science
Potato (Solanum tuberosum L.), a cornerstone of global food security, faces significant yield limitations worldwide. Fertilization regimes and planting density critically determine potato yield and quality.
Weiran Zhong   +3 more
doaj   +1 more source

Cardiovascular Disease: Analyzing Primary and Secondary Prevention Strategies [PDF]

open access: yes, 2018
Cardiovascular disease (CVD) is the single most common cause of death around the world, with an increasing number of people living with coronary heart disease (CHD) (Anderson et al., 2016).
Bohney, Michael   +3 more
core   +1 more source

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