Results 1 to 10 of about 108,758 (309)

Melatonin and Health: Insights of Melatonin Action, Biological Functions, and Associated Disorders

Cellular and Molecular Neurobiology, 2023
Melatonin is ubiquitous molecule with wide distribution in nature and is produced by many living organisms. In human beings, pineal gland is the major site for melatonin production and to lesser extent by retina, lymphocytes, bone marrow ...
Amir Wani, Aarif Ali, Shahzada Mudasir Rashid   +2 more
exaly   +2 more sources

Melatonin Effects on Glucose Metabolism: Time to Unlock the Controversy

Trends in Endocrinology and Metabolism, 2020
The last decade has witnessed a revival of the interest in the hormone melatonin, partly attributable to the discovery that variance in MTNR1B—the melatonin receptor 1b gene—is a risk factor for impaired fasting glucose and type-2-diabetes.
Jose C Florez, Frank A.J.L. Scheer, Marta Garaulet   +2 more
exaly   +2 more sources

Exogenous melatonin promotes seed germination and osmotic regulation under salt stress in cotton (Gossypium hirsutum L.).

PLoS ONE, 2020
Melatonin (MT; N-acetyI-5-methoxytryptamine) is an amine hormone involved in abiotic stress resistance. Previous studies have confirmed that melatonin can promote seed germination, mediate physiological regulation mechanisms, and stimulate crop growth ...
Li Chen, Liantao Liu, Bin Lu, Tongtong Ma, Dan Jiang, Jin Li, Ke Zhang, Hongchun Sun, Yongjiang Zhang, Zhiying Bai, Cundong Li   +10 more
doaj   +2 more sources

Anti-Inflammatory Comparison of Melatonin and Its Bromobenzoylamide Derivatives in Lipopolysaccharide (LPS)-Induced RAW 264.7 Cells and Croton Oil-Induced Mice Ear Edema

Molecules, 2021
The pineal gland is a neuroendocrine organ that plays an important role in anti-inflammation through the hormone melatonin. The anti-inflammatory effects of melatonin and its derivatives have been reported in both in vitro and in vivo models.
Pimpichaya Sangchart, Panyada Panyatip, Teerasak Damrongrungruang, Aroonsri Priprem, Pramote Mahakunakorn, Ploenthip Puthongking   +5 more
doaj   +1 more source

Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation

Microbiome, 2023
Background Sleep loss is a serious global health concern. Consequences include memory deficits and gastrointestinal dysfunction. Our previous research showed that melatonin can effectively improve cognitive impairment and intestinal microbiota ...
Xintong Wang, Zi-Xu Wang, Jing Cao, Yu-Lan Dong, Yao-Xing Chen   +4 more
semanticscholar   +1 more source

Polyphenol and Tryptophan Contents of Purple Corn (Zea mays L.) Variety KND and Butterfly Pea (Clitoria ternatea) Aqueous Extracts: Insights into Phytochemical Profiles with Antioxidant Activities and PCA Analysis

Plants, 2023
Plants are a rich source of phytochemical compounds with antioxidant activity. Several studies have revealed that the consumption of plant polyphenols reduces the risk of diseases. Purple corn (Zea mays L.
Juthamat Ratha, Chawalit Yongram, Panyada Panyatip, Patcharapol Powijitkul, Pimolwan Siriparu, Suthida Datham, Aroonsri Priprem, Tarapong Srisongkram, Ploenthip Puthongking   +8 more
doaj   +1 more source

Circadian Rhythm Dysregulation and Restoration: The Role of Melatonin

Nutrients, 2021
Sleep is an essential component of overall human health but is so tightly regulated that when disrupted can cause or worsen certain ailments. An important part of this process is the presence of the well-known hormone, melatonin. This compound assists in
Clayton Vasey, Jennifer McBride, K. Penta   +2 more
semanticscholar   +1 more source

Effect of Germination and Illumination on Melatonin and Its Metabolites, Phenolic Content, and Antioxidant Activity in Mung Bean Sprouts

Plants, 2022
Mung bean (Vigna radiata L.) sprouts are increasingly consumed and have become part of a healthy diet. The sprouts are composed of proteins, carbohydrates, and biochemical compounds.
Pimolwan Siriparu, Panyada Panyatip, Thanawat Pota, Juthamat Ratha, Chawalit Yongram, Tarapong Srisongkram, Bunleu Sungthong, Ploenthip Puthongking   +7 more
doaj   +1 more source

Melatonin-Mediated Abiotic Stress Tolerance in Plants

Frontiers in Plant Science, 2022
Melatonin is a multi-functional molecule that is ubiquitous in all living organisms. Melatonin performs essential roles in plant stress tolerance; its application can reduce the harmful effects of abiotic stresses.
Wengqin Zeng, S. Mostafa, Zhao-Geng Lu, B. Jin   +3 more
semanticscholar   +1 more source

Effect of N-Amide Substitution on Antioxidative Activities of Melatonin Derivatives

Scientia Pharmaceutica, 2020
Five N-amide substituted melatonin (MLT) derivatives were synthesized and evaluated for antioxidative activities, and compounds 9−12 showed higher electron spin resonance (ESR) response than MLT. 4-Bromobenzoyl and naphthoyl derivatives (10 and 11)
Panyada Panyatip, Nutjaree Pratheepawanit Johns, Aroonsri Priprem, Kouichi Nakagawa, Ploenthip Puthongking   +4 more
doaj   +1 more source