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Anti-Inflammatory Comparison of Melatonin and Its Bromobenzoylamide Derivatives in Lipopolysaccharide (LPS)-Induced RAW 264.7 Cells and Croton Oil-Induced Mice Ear Edema

open access: yesMolecules, 2021
The pineal gland is a neuroendocrine organ that plays an important role in anti-inflammation through the hormone melatonin. The anti-inflammatory effects of melatonin and its derivatives have been reported in both in vitro and in vivo models.
Pimpichaya Sangchart   +5 more
doaj   +1 more source

Polyphenol and Tryptophan Contents of Purple Corn (Zea mays L.) Variety KND and Butterfly Pea (Clitoria ternatea) Aqueous Extracts: Insights into Phytochemical Profiles with Antioxidant Activities and PCA Analysis

open access: yesPlants, 2023
Plants are a rich source of phytochemical compounds with antioxidant activity. Several studies have revealed that the consumption of plant polyphenols reduces the risk of diseases. Purple corn (Zea mays L.
Juthamat Ratha   +8 more
doaj   +1 more source

Effect of Germination and Illumination on Melatonin and Its Metabolites, Phenolic Content, and Antioxidant Activity in Mung Bean Sprouts

open access: yesPlants, 2022
Mung bean (Vigna radiata L.) sprouts are increasingly consumed and have become part of a healthy diet. The sprouts are composed of proteins, carbohydrates, and biochemical compounds.
Pimolwan Siriparu   +7 more
doaj   +1 more source

Effect of N-Amide Substitution on Antioxidative Activities of Melatonin Derivatives

open access: yesScientia Pharmaceutica, 2020
Five N-amide substituted melatonin (MLT) derivatives were synthesized and evaluated for antioxidative activities, and compounds 9−12 showed higher electron spin resonance (ESR) response than MLT. 4-Bromobenzoyl and naphthoyl derivatives (10 and 11)
Panyada Panyatip   +4 more
doaj   +1 more source

The effects of melatonin treatment on oxidative stress induced by ovariohysterectomy in dogs

open access: yesBMC Veterinary Research, 2021
Background As one of the most common surgeries performed in veterinary medicine, ovariohysterectomy (OHE) can induce oxidative stress in dogs. The antioxidant properties of melatonin have been confirmed in various studies. This study aimed to investigate
Sina Salavati   +4 more
doaj   +1 more source

Melatonin: Both a Messenger of Darkness and a Participant in the Cellular Actions of Non-Visible Solar Radiation of Near Infrared Light

open access: yesBiology, 2023
Throughout the history of melatonin research, almost exclusive focus has been on nocturnally-generated pineal melatonin production, which accounts for its circadian rhythm in the blood and cerebrospinal fluid; these light/dark melatonin cycles drive the ...
Dun-Xian Tan   +3 more
doaj   +1 more source

The effects of melatonin on the concentrations of inflammatory cytokines and proteins, serotonin, cortisol and melatonin in ovariohysterectomised female dogs

open access: yesVeterinary Medicine and Science, 2023
Background Ovariohysterectomy (OHE) induces inflammation and stress in female dogs. The anti‐inflammatory effects of melatonin have been reported in several studies.
Sina Salavati   +4 more
doaj   +1 more source

Melatonin Improves Cotton Salt Tolerance by Regulating ROS Scavenging System and Ca2 + Signal Transduction

open access: yesFrontiers in Plant Science, 2021
As one of the cash crops, cotton is facing the threat of abiotic stress during its growth and development. It has been reported that melatonin is involved in plant defense against salt stress, but whether melatonin can improve cotton salt tolerance and ...
Yuexin Zhang   +16 more
doaj   +1 more source

In vitro cytoprotective and in vivo anti-oral mucositis effects of melatonin and its derivatives [PDF]

open access: yesPeerJ
According to our preliminary study, melatonin and its N-amide derivatives (N-(2-(1-4-bromobenzoyl-5-methoxy-1H-indol-3-yl)ethyl)acetamide (BBM) and 4-bromo-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)benzamide (EBM)) inhibited the marker of acute inflammation in
Pramote Mahakunakorn   +6 more
doaj   +2 more sources

Melatonin Attenuates the Urea-Induced Yields Improvement Through Remodeling Transcriptome and Rhizosphere Microbial Community Structure in Soybean

open access: yesFrontiers in Microbiology, 2022
Foliar application of nitrogen to enhance crop productivity has been widely used. Melatonin is an effective regulator in promoting plant growth. However, the effects of melatonin and the combination of melatonin and nitrogen on soybeans yields production
Renhao Xiao   +9 more
doaj   +1 more source

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