Results 31 to 40 of about 64,266 (267)

Analysis of melatonin content and gene expression in Chinese cherry leaves [PDF]

E3S Web of Conferences, 2020
To investigate the accumulation characteristics and mechanism of melatonin in cherry leaves of different leaf ages, the melatonin content and the expression of synthetic genes in cherry leaves of different leaf ages were measured. The results showed that
Wang Xin, Shen Tian, Zhang Xuefeng, Hu Peng, Tu Hongxia, Zhou Gui-hong, Liang Dong, Xia Hui   +7 more
doaj   +1 more source

Cardiovascular Benefits of Dietary Melatonin: A Myth or a Reality?

Frontiers in Physiology, 2018
The role of the diet as well as the impact of the dietary habits on human health and disease is well established. Apart from its sleep regulatory effect, the indoleamine melatonin is a well-established antioxidant molecule with multiple health benefits ...
Zukiswa Jiki, Sandrine Lecour, Frederic Nduhirabandi   +2 more
doaj   +1 more source

Melatonin Mitigates Chilling-Induced Oxidative Stress and Photosynthesis Inhibition in Tomato Plants

Antioxidants, 2020
Melatonin has been demonstrated to play a variety of roles in plants. Of particular importance is its role as a potent antioxidative agent. In the present study, we generated melatonin-deficient tomato plants using virus-induced gene silencing (VIGS ...
Meiling Wang, Shuoxin Zhang, Fei Ding
doaj   +1 more source

Melatonin combined with endoplasmic reticulum stress induces cell death via the PI3K/Akt/mTOR pathway in B16F10 melanoma cells.

PLoS ONE, 2014
This study investigated B16F10 melanoma cell death induced by melatonin combined with endoplasmic reticulum (ER) stress through the PI3K/Akt/mTOR pathway.
Han Sung Kim, Tack-Joong Kim, Yeong-Min Yoo   +2 more
doaj   +1 more source

Melatonin Reverses the Warburg-Type Metabolism and Reduces Mitochondrial Membrane Potential of Ovarian Cancer Cells Independent of MT1 Receptor Activation

Molecules, 2022
Ovarian cancer (OC) is the most lethal gynecologic malignancy, and melatonin has shown various antitumor properties. Herein, we investigated the influence of melatonin therapy on energy metabolism and mitochondrial integrity in SKOV-3 cells and tested ...
Maira Smaniotto Cucielo, Roberta Carvalho Cesário, Henrique Spaulonci Silveira, Letícia Barbosa Gaiotte, Sérgio Alexandre Alcantara dos Santos, Debora Aparecida Pires de Campos Zuccari, Fábio Rodrigues Ferreira Seiva, Russel J. Reiter, Luiz Gustavo de Almeida Chuffa   +8 more
doaj   +1 more source

Melatonin reduces intramuscular fat deposition by promoting lipolysis and increasing mitochondrial function

Journal of Lipid Research, 2019
In obesity and diabetes, intramuscular fat (IMF) content correlates markedly with insulin sensitivity, which makes IMF manipulation an area of therapeutic interest.
Kaiqing Liu, Wensai Yu, Wei Wei, Xinbao Zhang, Ye Tian, Melak Sherif, Xin Liu, Chao Dong, Wangjun Wu, Lifan Zhang, Jie Chen   +10 more
doaj   +1 more source

Inhibition of α-glucosidase by melatonin derivatives: insights from kinetics, docking, and molecular dynamics simulations

Medicine in Drug Discovery
Type 2 diabetes mellitus (T2DM) represents a major global health challenge, emphasizing the need for effective strategies to manage postprandial hyperglycemia.
Ploenthip Puthongking, Bodee Nutho, Muhammad Subhan, Juthamat Ratha, Kiattawee Choowongkomon, Saranyu Khammuang, Kamonpan Sanachai   +6 more
doaj   +1 more source

Behavioral changes in the brown planthopper, Nilaparvata lugens, mediated by melatonin

CABI Agriculture and Bioscience, 2021
Background Melatonin has been proved to exist and play importance roles in rice plant, such as biosynthesis and resistance. However, little is known about the function of melatonin in its monophagous pest, the brown planthopper. Methods In this study, we
Longqing Shi, Junian Zhang, Liangmiao Qiu, Zhaowei Jiang, Zhenxing Xie, Zhixiong Zhan   +5 more
doaj   +1 more source

Molecular Regulation of Antioxidant Melatonin Biosynthesis by Brassinosteroid Acting as an Endogenous Elicitor of Melatonin Induction in Rice Seedlings

Antioxidants, 2022
Gibberellic acid (GA) was recently shown to induce melatonin synthesis in rice. Here, we examined whether brassinosteroids (BRs) also induce melatonin synthesis because BRs and GA show redundancy in many functions. Among several plant hormones, exogenous
Ok Jin Hwang, Kyoungwhan Back
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source