Results 31 to 40 of about 92,984 (317)

Modulation of melatonin to the thalamic lesion-induced pain and comorbid sleep disturbance in the animal model of the central post-stroke hemorrhage

open access: yesMolecular Pain, 2022
The devastating chronic central post stroke pain is associated with variety of comorbidities. Disrupted sleep is a severe comorbidity, causing an increase in the suicide rate, due to CPSP’s pain symptom.
Tavleen Kaur   +3 more
doaj   +1 more source

Melatonin and Epilepsy [PDF]

open access: yesFolia Medica, 2021
Epilepsy is a chronic neurological disease with recurrent seizures. Its incidence, the social and psychological aspects of epilepsy-associated stigmatization in society, the medical risk of severe seizures, and the challenges in treatment confirm its medical and social significance.
openaire   +3 more sources

The role of melatonin in the development of postmenopausal osteoporosis

open access: yesFrontiers in Pharmacology, 2022
Melatonin is an important endogenous hormone that modulates homeostasis in the microenvironment. Recent studies have indicated that serum melatonin levels are closely associated with the occurrence and development of osteoporosis in postmenopausal women.
Keda Yang   +3 more
doaj   +1 more source

Effects of long-term light, darkness and oral administration of melatonin on serum levels of melatonin

open access: yesBiomedical Journal, 2016
Background: Continuous light or darkness has various effects on different systems. In the present research work, the effects of constant light and darkness exposure of male rats and oral administration of exogenous melatonin on the serum levels of ...
Naser Farhadi   +2 more
doaj   +1 more source

Melatonin Mitigates Chilling-Induced Oxidative Stress and Photosynthesis Inhibition in Tomato Plants

open access: yesAntioxidants, 2020
Melatonin has been demonstrated to play a variety of roles in plants. Of particular importance is its role as a potent antioxidative agent. In the present study, we generated melatonin-deficient tomato plants using virus-induced gene silencing (VIGS ...
Meiling Wang, Shuoxin Zhang, Fei Ding
doaj   +1 more source

The effects of acute melatonin supplementation on central and peripheral responses in healthy humans during sympathetic stimuli [PDF]

open access: yes, 2023
There is evidence that melatonin has more functions other than regulating sleeping tendencies such as anti-hypertensive and antioxidant functions, however how melatonin exerts these functions is unknown.
Skillett, Sarah
core  

The hormonal Zeitgeber melatonin: role as a circadian modulator in memory processing

open access: yes, 2012
The neuroendocrine substance melatonin is a hormone synthesized rhythmically by the pineal gland under the influence of the circadian system and alternating light/dark cycles. Melatonin has been shown to have broad applications, and consequently becoming
Rawashdeh, Oliver   +5 more
core   +1 more source

Melatonin combined with endoplasmic reticulum stress induces cell death via the PI3K/Akt/mTOR pathway in B16F10 melanoma cells.

open access: yesPLoS ONE, 2014
This study investigated B16F10 melanoma cell death induced by melatonin combined with endoplasmic reticulum (ER) stress through the PI3K/Akt/mTOR pathway.
Han Sung Kim   +2 more
doaj   +1 more source

Cardiovascular Benefits of Dietary Melatonin: A Myth or a Reality?

open access: yesFrontiers in Physiology, 2018
The role of the diet as well as the impact of the dietary habits on human health and disease is well established. Apart from its sleep regulatory effect, the indoleamine melatonin is a well-established antioxidant molecule with multiple health benefits ...
Zukiswa Jiki   +2 more
doaj   +1 more source

Understanding the role of melatonin in cancer metabolism [PDF]

open access: yes, 2019
Oncogenes alters metabolic pathways while the resulted metabolites, in turn, modifies the expression and production of oncogenes or tumor suppressors.
Rodríguez González, Pablo   +6 more
core   +1 more source

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