Cellular Basis of Pineal Gland Development: Emerging Role of Microglia as Phenotype Regulator. [PDF]
PLoS ONE, 2016 The adult pineal gland is composed of pinealocytes, astrocytes, microglia, and other interstitial cells that have been described in detail. However, factors that contribute to pineal development have not been fully elucidated, nor have pineal cell ...
María P Ibañez Rodriguez +2 more
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Reduced Pineal Gland Volume in Oncology Patients: Association with Chemotherapy Duration [PDF]
MedicinaBackground and Objectives: The pineal gland is a neuroendocrine structure whose function can be disrupted in patients with malignancies. This study examines the differences in pineal gland volume between oncology patients and healthy controls, as well as
Milica Šarošković +4 more
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Prevalence of pineal gland calcification: systematic review and meta-analysis [PDF]
Systematic Reviews, 2023 Background Pineal gland calcification is the formation of corpora arenacea predominantly composed of calcium and phosphorus. It plays an important role in regulating the light/dark circadian changes to synchronize their daily physiological activities ...
Daniel Gashaneh Belay +1 more
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Pineal gland volume loss in females with multiple sclerosis [PDF]
Frontiers in NeuroanatomyIntroductionMultiple sclerosis has a complex pathophysiology, and numerous risk factors can contribute to its development, like exposure to sunlight that is associated with serum levels of melatonin.
Miloš Vuković +7 more
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Utility of 18F-FDG PET/CT in Detecting Spinal Drop Metastases from Pineal Gland Tumors [PDF]
Asia Oceania Journal of Nuclear Medicine and BiologyPineal gland tumors are significant despite being rare (
Kabilash Dhayalan +3 more
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Molecules, 2018 The pineal gland is a unique organ that synthesizes melatonin as the signaling molecule of natural photoperiodic environment and as a potent neuronal protective antioxidant.
Russel J Reiter, Dun Xian Tan
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Morphology of the Human Pineal Gland Studied by Freeze-Fracturing in Scanning Electron Microscopy [PDF]
LifeThe human pineal gland is the largest producer of the hormone melatonin. Pineal acervuli (brain sand), calcified concretions in the pineal gland, have long been studied because of their association with ageing, melatonin production, and neurological ...
Simona Polakovičová +3 more
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Pineal gland cyst and ADHD in a juvenile patient: a case report [PDF]
European PsychiatryIntroduction The role of the pineal gland in psychiatric disorders is poorly investigated. There are studies, primarily on adult patients, that indicate a higher presence of pineal gland abnormalities in patients suffering from depression, schizophrenia
A. Kovačević +8 more
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Pineal Gland from the Cell Culture to Animal Models: A Review
Life, 2022 This review demonstrates current literature on pineal gland physiology, pathology, and animal model experiments to concisely explore future needs in research development with respect to pineal gland function and neuro-regenerative properties.
Alekhya Peruri +14 more
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AAV vectors accumulate in the pineal gland after injections into the brain or spinal cord
Molecular Therapy: Methods & Clinical Development, 2021 AAV vectors are being used extensively for gene-modifying therapies for neurological disorders. Here, we report the surprising discovery that injections of different AAVs into the brain, spinal cord, or cerebrospinal fluid (CSF) lead to robust ...
Oswald Steward +4 more
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