Results 31 to 40 of about 19,371 (184)
Content of microelements in the rat pineal gland at different ages and the effects of selenium supplementation [PDF]
The mammalian pineal gland regulates a number of important physiological processes. In this paper we report changes in the content of iron (Fe), zinc (Zn), copper (Cu), and selenium (Se) in the male rat pineal glands at 4, 5, 8, and 12 months of age. The
Demajo M. +2 more
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Biosynthesis and biological action of pineal allopregnanolone
The pineal gland transduces photoperiodic changes to the neuroendocrine system by rhythmic secretion of melatonin. We recently provided new evidence that the pineal gland is a major neurosteroidogenic organ and actively produces a variety of ...
Kazuyoshi eTsutsui, Shogo eHaraguchi
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Glia-pinealocyte network: the paracrine modulation of melatonin synthesis by tumor necrosis factor (TNF). [PDF]
The pineal gland, a circumventricular organ, plays an integrative role in defense responses. The injury-induced suppression of the pineal gland hormone, melatonin, which is triggered by darkness, allows the mounting of innate immune responses.
Sanseray da Silveira Cruz-Machado +4 more
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PINEAL GLAND IN PEDIATRICS [PDF]
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openaire +2 more sources
Profiling Temporal Changes of the Pineal Transcriptomes at Single Cell Level Upon Neonatal HIBD
Neonatal hypoxic-ischemic brain damage (HIBD) often results in various neurological deficits. Among them, a common, yet often neglected, symptom is circadian rhythm disorders. Previous studies revealed that the occurrence of cysts in the pineal gland, an
Xin Ding +14 more
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Macro-microscopical aspects of the buffalo (Bubalus bubalis Linnaeus, 1758) pineal gland [PDF]
Gross and microscopical aspects of the buffalo pineal gland were described in seasonal parturition animals, since this gland is responsible for melatonin secretion which acts upon the hypothalamus-hypophysis reproductive axis feedback system.
Ana Flávia de Carvalho +4 more
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Melatonin Levels in 89 Individuals With Smith Magenis Syndrome
ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
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ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo +3 more
wiley +1 more source
Pineal Gland Volume in Major Depressive and Bipolar Disorders
Abnormal melatonin secretion has been demonstrated in patients with affective disorders such as major depressive disorder (MDD) and bipolar disorder (BD).
Tsutomu Takahashi +12 more
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IntroductionPineal gland tumors are exceedingly rare and account for 0.4-1.0% of brain neoplasms. Their rarity has confounded a clear understanding of the prognostic factors and standards of care for these neoplasms.
Huy Gia Vuong +3 more
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