Results 31 to 40 of about 19,371 (184)

Content of microelements in the rat pineal gland at different ages and the effects of selenium supplementation [PDF]

open access: yesArchives of Biological Sciences, 2006
The mammalian pineal gland regulates a number of important physiological processes. In this paper we report changes in the content of iron (Fe), zinc (Zn), copper (Cu), and selenium (Se) in the male rat pineal glands at 4, 5, 8, and 12 months of age. The
Demajo M.   +2 more
doaj   +1 more source

Biosynthesis and biological action of pineal allopregnanolone

open access: yesFrontiers in Cellular Neuroscience, 2014
The pineal gland transduces photoperiodic changes to the neuroendocrine system by rhythmic secretion of melatonin. We recently provided new evidence that the pineal gland is a major neurosteroidogenic organ and actively produces a variety of ...
Kazuyoshi eTsutsui, Shogo eHaraguchi
doaj   +1 more source

Glia-pinealocyte network: the paracrine modulation of melatonin synthesis by tumor necrosis factor (TNF). [PDF]

open access: yesPLoS ONE, 2012
The pineal gland, a circumventricular organ, plays an integrative role in defense responses. The injury-induced suppression of the pineal gland hormone, melatonin, which is triggered by darkness, allows the mounting of innate immune responses.
Sanseray da Silveira Cruz-Machado   +4 more
doaj   +1 more source

PINEAL GLAND IN PEDIATRICS [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1920
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openaire   +2 more sources

Profiling Temporal Changes of the Pineal Transcriptomes at Single Cell Level Upon Neonatal HIBD

open access: yesFrontiers in Cell and Developmental Biology, 2022
Neonatal hypoxic-ischemic brain damage (HIBD) often results in various neurological deficits. Among them, a common, yet often neglected, symptom is circadian rhythm disorders. Previous studies revealed that the occurrence of cysts in the pineal gland, an
Xin Ding   +14 more
doaj   +1 more source

Macro-microscopical aspects of the buffalo (Bubalus bubalis Linnaeus, 1758) pineal gland [PDF]

open access: yesBiotemas, 2009
Gross and microscopical aspects of the buffalo pineal gland were described in seasonal parturition animals, since this gland is responsible for melatonin secretion which acts upon the hypothalamus-hypophysis reproductive axis feedback system.
Ana Flávia de Carvalho   +4 more
doaj   +2 more sources

Melatonin Levels in 89 Individuals With Smith Magenis Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley   +1 more source

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo   +3 more
wiley   +1 more source

Pineal Gland Volume in Major Depressive and Bipolar Disorders

open access: yesFrontiers in Psychiatry, 2020
Abnormal melatonin secretion has been demonstrated in patients with affective disorders such as major depressive disorder (MDD) and bipolar disorder (BD).
Tsutomu Takahashi   +12 more
doaj   +1 more source

Incidence, Prognostic Factors, and Survival Trend in Pineal Gland Tumors: A Population-Based Analysis

open access: yesFrontiers in Oncology, 2021
IntroductionPineal gland tumors are exceedingly rare and account for 0.4-1.0% of brain neoplasms. Their rarity has confounded a clear understanding of the prognostic factors and standards of care for these neoplasms.
Huy Gia Vuong   +3 more
doaj   +1 more source

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