Results 51 to 60 of about 19,371 (184)

Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome

open access: yesAndrology, EarlyView.
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor   +6 more
wiley   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

open access: yesAndrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis   +3 more
wiley   +1 more source

Basal body temperature as a biomarker of reproductive state in ewes: A multi‐method comparison

open access: yesAustralian Veterinary Journal, EarlyView.
This study quantified body temperature dynamics throughout reproductive stages in crossbred ewes based on complementary monitoring techniques. Five ewes from a semi‐extensive farming system were included in two sub‐trials: animals were first assessed in the prepubertal stage and, subsequently, an oestrous cycle was induced by intravaginal progesterone ...
E Pérez‐García   +4 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Investigation of Misleading Techniques Used in Online Fluoride Misinformation

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives Fluoride misinformation can fuel anti‐fluoridation movements, influencing political decisions and dental treatment choices. This study aimed to elucidate the misleading techniques used to produce online fluoride misinformation. Methodology Two independent investigators searched scientific databases for references that supported or ...
Matheus Lotto   +4 more
wiley   +1 more source

Diurnal Variation and Impairment of Postprandial Glucose‐Insulin Responses and Lipid Rhythms in Simulated Shift Work

open access: yesNutrition Bulletin, EarlyView.
ABSTRACT Shift work is associated with insulin resistance, dyslipidaemia and metabolic syndrome, but how consecutive meals at the same clock times differentially shape postprandial metabolism in day‐ and night‐shifts remains unclear. This study used a unique simulated shift work intervention with four consecutive meals and high‐resolution sampling to ...
Ameena M. Khan Sullivan   +4 more
wiley   +1 more source

Low-grade oligodendroglioma of the pineal gland: a case report and review of the literature

open access: yesDiagnostic Pathology, 2010
Background Gliomas are a very rare subtype of pineal region tumours, whereas oligodendrogliomas of the pineal region are exceedingly rare, since there have been only 3 cases of anaplastic oligodedrogliomas reported this far.
Levidou Georgia   +5 more
doaj   +1 more source

The effects of spectrum, irradiance, and duration of exposure on light‐induced melatonin suppression in healthy adults

open access: yesPhotochemistry and Photobiology, EarlyView.
The left panel reports the measured time course data of melatonin concentration in the blood plasma of 17 BL‐Rs and 15 BL‐NRs at baseline, during a two‐hour stay in the dark, during a one‐hour light exposure to blue light, and again in the dark. The right panel shows the magnitude of melatonin concentration after 60 min of exposure to warm white, cool ...
Helmut Piazena   +4 more
wiley   +1 more source

Bone biology in aging periodontal and peri‐implant tissues

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Periodontal disease is an age‐related chronic inflammatory condition leading to tooth loss. Dental implants are an option for replacement of lost teeth in older adults. However, age‐related changes to alveolar bone may have pathological implications for its role in supporting the dentition and dental implants.
Dalia Rasheed Issa   +2 more
wiley   +1 more source

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