Results 71 to 80 of about 204,136 (221)

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

Low-grade oligodendroglioma of the pineal gland: a case report and review of the literature

Diagnostic Pathology, 2010
Background Gliomas are a very rare subtype of pineal region tumours, whereas oligodendrogliomas of the pineal region are exceedingly rare, since there have been only 3 cases of anaplastic oligodedrogliomas reported this far.
Levidou Georgia, Korkolopoulou Penelope, Agrogiannis George, Paidakakos Nikolaos, Bouramas Dimos, Patsouris Efstratios   +5 more
doaj   +1 more source

Dietary melatonin and its benefits on cardiovascular disease

British Journal of Pharmacology, EarlyView.
Cardiovascular disease remains the leading cause of mortality globally, with a disproportionate burden in low‐ and middle‐income countries. Melatonin, a hormone primarily produced by the pineal gland, exhibits notable antioxidant, anti‐inflammatory and immunomodulatory properties that may confer cardiovascular benefits.
Karabo Tisane, Carmelita Abrahams, Sandrine Lecour   +2 more
wiley   +1 more source

Diagnostic Yield of Brain MRI in Pediatric Short Stature: Hypothalamic–Pituitary Lesions and Incidental Findings in Real‐World Practice

Clinical Endocrinology, EarlyView.
ABSTRACT Background Brain MRI is widely performed in children with short stature or suspected growth hormone deficiency(GHD) to exclude hypothalamic–pituitary (HP) pathology, yet its diagnostic yield in routine practice is uncertain. We aimed to evaluate the prevalence, clinical significance, and distribution of HP and extrahypothalamic abnormalities ...
Mustafa Zubeidat, Tamer Sobeh, Shai Shrot   +2 more
wiley   +1 more source

Pineal gland

, 1997
Pineal gland. Mesencephalon-superior colliculus. Transverse plane.

core  

Pineal gland research with high resolution 3D imaging techniques

, 2020
The pineal gland is an endocrine gland in the brain, which produces melatonin under the control of the central clock and the suprachiasmatic nucleus [1].
Buzmakov A, Cedola A, Fratini M, Bukreeva I, Palermo F, Chukalina M, A Ingacheva, Asadchikov V   +7 more
core  

Neuromodulation of the Pineal Gland via Electrical Stimulation of Its Sympathetic Innervation Pathway

Frontiers in Neuroscience, 2020
Stimulation of the pineal gland via its sympathetic innervation pathway results in the production of N-acetylserotonin and melatonin. Melatonin has many therapeutic roles and is heavily implicated in the regulation of the sleep-wake cycle. In addition, N-
Susannah C. Lumsden, Susannah C. Lumsden, Andrew N. Clarkson, Andrew N. Clarkson, Andrew N. Clarkson, Yusuf Ozgur Cakmak, Yusuf Ozgur Cakmak, Yusuf Ozgur Cakmak, Yusuf Ozgur Cakmak   +8 more
doaj   +1 more source

Protein and mRNA expression of estradiol receptors during estrus in yaks (Bos grunniens)

Revista Brasileira de Zootecnia, 2015
The objective of this study was to investigate mRNA by real-time PCR and protein expression by immunofluorescence of the estradiol receptors (ER) in the pineal gland, hypothalamus, pituitary gland, and gonads of yaks (Bos grunniens).
Shengdong Huo, Qijian Yuan, Taojie Zhang, Junlin Liu, Ayimuguli Abudureyimu, Jutian Yang   +5 more
doaj   +1 more source

Human cerebral arterial morphogenesis explored by 3D microscopic imaging of cleared embryos: Bridging the gap between embryonic and adult anatomy

Journal of Anatomy, EarlyView.
We provide a description of human embryonic cerebral arterial development based on whole‐mount immunostaining, tissue clearing, three‐dimensional (3D) light‐sheet microscopy imaging, and anatomically informed virtual segmentation of human embryos. Findings are compared with adult radiological anatomy. We provide a detailed account of the development of
Eimad Shotar, Raphaël Blain, Aymeric Nadjem, Nermine Saidi, Megumi Inoue, Daniel Smith‐Paredes, Miccaella Vergara, Armelle Lesaunier, Quentin Rappeneau, Joséphine Blevinal, Gérard Couly, Julien Burel, Julien Allard, Kevin Premat, Stéphanie Lenck, Pierre‐Marie Chiaroni, Erwah Kalsoum, Maryne Toupin, Séverine Mazaud‐Guittot, Diane Rebourcet, Paolo Giacobini, Olivier Naggara, Hugo Gortais, Grégoire Boulouis, Alexis Guédon, Philippe Gailloud, Frédéric Glicenstein, Anaïs Favre, Frédéric Clarençon, Yorick Gitton, Alain Chédotal   +30 more
wiley   +1 more source

Temporal–spatial characterization of chicken clock genes: circadian expression in retina, pineal gland, and peripheral tissues

, 2003
The molecular core of the vertebrate circadian clock is a set of clock genes, whose products interact to control circadian changes in physiology. These clock genes are expressed in all tissues known to possess an endogenous self-sustaining clock, and ...
Chaurasia, S.S., Shyam S. Chaurasia, Haque, R., Rashidul Haque, Iuvone, P.M., Chong, Nelson W., David C. Klein, Nelson W. Chong, P. Michael Iuvone, Klein, D.C.   +9 more
core   +1 more source