Results 81 to 90 of about 191,019 (230)
PINEAL GLAND VOLUME IN SCHIZOPHRENIA AND MOOD DISORDERS [PDF]
, 2015 Background: The majority of patients with schizophrenia and mood disorders have disruptions in sleep and circadian rhythm. Melatonin, which is secreted by the human pineal gland, plays an important role in sleep and circadian rhythm.
Altun, Hatice +5 more
core +3 more sources
Frontiers in Neuroscience, 2020 Stimulation of the pineal gland via its sympathetic innervation pathway results in the production of N-acetylserotonin and melatonin. Melatonin has many therapeutic roles and is heavily implicated in the regulation of the sleep-wake cycle. In addition, N-
Susannah C. Lumsden +8 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The calcium‐activated chloride (ClCa) channel TMEM16A (also known as ANO1) plays critical roles in ion transport, neurotransmission and smooth muscle contraction. Dysregulation of TMEM16A channel activity contributes to the development and progression of various diseases.
Hisao Yamamura +4 more
wiley +1 more source
Innervation of the pineal gland in the rat: A chromotolysis study
مجله كليه طب الكندي, 2011 Back ground: The innervations of the pineal gland from the superior cervical ganglion have shown some form of a chromatolysis reaction. Objective: 1-Tracing the innervations of the pineal gland by removing the target tissue (the pineal gland in this ...
Hadi J. Ali
doaj
, 2014 Although the pineal gland (epiphysis cerebri) has been noted in medical writings for at least 2,000 years its possible physiological role remains unresolved.
Hamilton, Thomas
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani +5 more
wiley +1 more source
Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
Multimodal treatment of pineal metastasis from oesophageal adenocarcinoma
Drugs in ContextThe pineal gland is a neuroendocrine gland located in the epithalamus. Primary pineal tumours are uncommon and metastatic cancer spreading to the pineal gland is even more unusual.
Francesca Rifaldi +17 more
doaj +1 more source
Protein and mRNA expression of estradiol receptors during estrus in yaks (Bos grunniens)
Revista Brasileira de Zootecnia, 2015 The objective of this study was to investigate mRNA by real-time PCR and protein expression by immunofluorescence of the estradiol receptors (ER) in the pineal gland, hypothalamus, pituitary gland, and gonads of yaks (Bos grunniens).
Shengdong Huo +5 more
doaj +1 more source
Melatonin Levels in 89 Individuals With Smith Magenis Syndrome
American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2260-2272, October 2026.ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley +1 more source