Results 81 to 90 of about 41,160 (231)

Investigating the protective role of the natural hormone Melatonin, in reducing drug-induced cardiotoxicity in the therapy of chronic diseases [PDF]

open access: yes, 2019
Heart failure (HF) is a highly complex disorder and a major end-point of cardiovascular diseases (CVD). The pathogenesis of HF is mostly unresolved but involves interplay between cardiac structural and electrical remodelling, metabolic alterations, cell ...
Kasi Ganeshan, T., Kasi Ganeshan, T.
core  

Cytoprotective effects of melatonin against amitriptyline-induced toxicity in isolated rat hepatocytes [PDF]

open access: yes, 2015
Purpose: Amitriptyline, one of the commonly used tricyclic antidepressants, caused rare but severe hepatotoxicity in patients who received it continuously. Previous findings showed that the intermediate metabolites of amitriptyline produced by CYP450 are
Dastmalchi, S.   +3 more
core   +1 more source

The Effect of 6 Months of Dietary Counselling on Sleep Outcomes Among Patients With Cardiovascular Diseases: A Randomised Controlled Trial

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Sleep problems are highly prevalent among patients with cardiovascular diseases (CVD). We examined the effect of dietary counselling on sleep outcomes among patients with CVD. We performed secondary analyses within a previously conducted six‐month randomised controlled trial among patients with CVD.
Auke J. C. F. Verkaar   +5 more
wiley   +1 more source

Neuromodulation of the Pineal Gland via Electrical Stimulation of Its Sympathetic Innervation Pathway

open access: yesFrontiers in Neuroscience, 2020
Stimulation of the pineal gland via its sympathetic innervation pathway results in the production of N-acetylserotonin and melatonin. Melatonin has many therapeutic roles and is heavily implicated in the regulation of the sleep-wake cycle. In addition, N-
Susannah C. Lumsden   +8 more
doaj   +1 more source

Pineal [PDF]

open access: yes, 2009
Histology blog entry for January 30, 2009 about the pineal ...
Krause, William J., II, 1942-
core  

OsMYB306‐OsRAV11 Regulates Resistance of Rice to Striped Stem Borer by Modulating Serotonin Biosynthesis

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Striped stem borer (SSB; Chilo suppressalis Walker) is one of the most destructive pests in rice production. Previous studies have demonstrated that SSB infestation induces transcription of OsT5H (tryptamine‐5‐hydroxylase) and biosynthesis of serotonin, a newly recognised phytohormone, and that disruption of serotonin biosynthesis ...
Jia‐Run Zhang   +9 more
wiley   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

open access: yesPhotochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza   +4 more
wiley   +1 more source

Protein and mRNA expression of estradiol receptors during estrus in yaks (Bos grunniens)

open access: yesRevista Brasileira de Zootecnia, 2015
The objective of this study was to investigate mRNA by real-time PCR and protein expression by immunofluorescence of the estradiol receptors (ER) in the pineal gland, hypothalamus, pituitary gland, and gonads of yaks (Bos grunniens).
Shengdong Huo   +5 more
doaj   +1 more source

Circadian clocks and breast cancer [PDF]

open access: yes, 2016
Circadian clocks respond to environmental time cues to coordinate 24-hour oscillations in almost every tissue of the body. In the breast, circadian clocks regulate the rhythmic expression of numerous genes.
Blakeman, V   +3 more
core   +2 more sources

The effects of spectrum, irradiance, and duration of exposure on light‐induced melatonin suppression in healthy adults

open access: yesPhotochemistry and Photobiology, EarlyView.
The left panel reports the measured time course data of melatonin concentration in the blood plasma of 17 BL‐Rs and 15 BL‐NRs at baseline, during a two‐hour stay in the dark, during a one‐hour light exposure to blue light, and again in the dark. The right panel shows the magnitude of melatonin concentration after 60 min of exposure to warm white, cool ...
Helmut Piazena   +4 more
wiley   +1 more source

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