Results 11 to 20 of about 19,371 (184)

AAV vectors accumulate in the pineal gland after injections into the brain or spinal cord

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
AAV vectors are being used extensively for gene-modifying therapies for neurological disorders. Here, we report the surprising discovery that injections of different AAVs into the brain, spinal cord, or cerebrospinal fluid (CSF) lead to robust ...
Oswald Steward   +4 more
doaj   +1 more source

Pineal gland: structural variants and their role in neurological and psychiatric disorders [PDF]

open access: yesАнналы клинической и экспериментальной неврологии, 2022
The pineal gland is a small and poorly studied neuroendocrine gland located in the epithalamus. There is growing interest in the pineal gland due to its role in regulating human biological rhythms, which is associated with melatonin production, and its ...
Anastasia V. Shilova   +3 more
doaj   +1 more source

Effects of different light intensities on the transcriptome changes of duck retina and pineal gland

open access: yesPoultry Science, 2022
: The light intensity can affect the production performance of animals. The retina and pineal gland, closely linked, are directly photosensitive organs.
Jingjing Qi   +12 more
doaj   +1 more source

Pineal gland calcification confirmed by CT scan is associated with ischemic stroke [PDF]

open access: yesRomanian Journal of Neurology, 2019
Background. Stroke is the second leading cause of death and the most common debilitating neurological disorder worldwide. The ischemic injury causes inflammation and oxidative stress, and leads to apoptosis, necrosis and activation of autophagal pathways
Yaser Moadabi   +5 more
doaj   +1 more source

CLINICAL AND MORPHOLOGICAL CORRELATES OF PINEAL GLAND FUNCTION IN INFANTS WITH EXTREMELY LOW BODY WEIGHT

open access: yesНеонатологія, хірургія та перинатальна медицина, 2022
Introduction. The functional activity of the pineal gland plays a dramatic important role in the adaptation to postnatal life and in the pathogenesis of the most common perinatal pathology of premature infants. The aim of the study.
Т. Клименко   +1 more
doaj   +1 more source

Fluoride and Pineal Gland [PDF]

open access: yesApplied Sciences, 2020
The pineal gland is an endocrine gland whose main function is the biosynthesis and secretion of melatonin, a hormone responsible for regulating circadian rhythms, e.g., the sleep/wake cycle. Due to its exceptionally high vascularization and its location outside the blood–brain barrier, the pineal gland may accumulate significant amounts of calcium and ...
Dariusz Chlubek, Maciej Sikora
openaire   +2 more sources

Transcriptome Analysis of Pineal Glands in the Mouse Model of Alzheimer’s Disease

open access: yesFrontiers in Molecular Neuroscience, 2020
The pineal gland maintains the circadian rhythm in the body by secreting the hormone melatonin. Alzheimer’s disease (AD) is the most common neurodegenerative disease. Pineal gland impairment in AD is widely observed, but no study to date has analyzed the
Kwang Il Nam   +6 more
doaj   +1 more source

Potential contribution of pineal atrophy and pineal cysts toward vulnerability and clinical characteristics of psychosis

open access: yesNeuroImage: Clinical, 2021
Background: Magnetic resonance imaging (MRI) studies reported pineal gland atrophy in schizophrenia patients and individuals at a clinical high risk of developing psychosis, implicating abnormalities in melatonin secretion in the pathophysiology of ...
Tsutomu Takahashi   +11 more
doaj   +1 more source

The pineal gland and reproduction [PDF]

open access: yesHuman Reproduction Update, 1996
The hormonal activity of the pineal gland is influenced by both the dark-light cycle and the seasonal cycle, causing it to play an important role in the neuroendocrine control of reproductive physiology. This is especially evident in seasonally breeding animals, in which reproductive function is clearly influenced by seasonal variations in the duration
ALEANDRI, Vincenzo   +2 more
openaire   +3 more sources

PRE-NATAL DEVELOPMENT OF THE PINEAL GLAND OF ALBINO RAT [PDF]

open access: yesAssiut Veterinary Medical Journal, 1984
The pre-natal development of the pineal gland of albino rats was studied. In 131/2 days old-embryo, the pineal gland ap < /strong>peared as an evagination from the floor of the third ven tricle.
R.S. MOHAMMED   +3 more
doaj   +1 more source

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