Results 11 to 20 of about 19,371 (184)
AAV vectors accumulate in the pineal gland after injections into the brain or spinal cord
AAV vectors are being used extensively for gene-modifying therapies for neurological disorders. Here, we report the surprising discovery that injections of different AAVs into the brain, spinal cord, or cerebrospinal fluid (CSF) lead to robust ...
Oswald Steward +4 more
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Pineal gland: structural variants and their role in neurological and psychiatric disorders [PDF]
The pineal gland is a small and poorly studied neuroendocrine gland located in the epithalamus. There is growing interest in the pineal gland due to its role in regulating human biological rhythms, which is associated with melatonin production, and its ...
Anastasia V. Shilova +3 more
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Effects of different light intensities on the transcriptome changes of duck retina and pineal gland
: The light intensity can affect the production performance of animals. The retina and pineal gland, closely linked, are directly photosensitive organs.
Jingjing Qi +12 more
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Pineal gland calcification confirmed by CT scan is associated with ischemic stroke [PDF]
Background. Stroke is the second leading cause of death and the most common debilitating neurological disorder worldwide. The ischemic injury causes inflammation and oxidative stress, and leads to apoptosis, necrosis and activation of autophagal pathways
Yaser Moadabi +5 more
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Introduction. The functional activity of the pineal gland plays a dramatic important role in the adaptation to postnatal life and in the pathogenesis of the most common perinatal pathology of premature infants. The aim of the study.
Т. Клименко +1 more
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Fluoride and Pineal Gland [PDF]
The pineal gland is an endocrine gland whose main function is the biosynthesis and secretion of melatonin, a hormone responsible for regulating circadian rhythms, e.g., the sleep/wake cycle. Due to its exceptionally high vascularization and its location outside the blood–brain barrier, the pineal gland may accumulate significant amounts of calcium and ...
Dariusz Chlubek, Maciej Sikora
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Transcriptome Analysis of Pineal Glands in the Mouse Model of Alzheimer’s Disease
The pineal gland maintains the circadian rhythm in the body by secreting the hormone melatonin. Alzheimer’s disease (AD) is the most common neurodegenerative disease. Pineal gland impairment in AD is widely observed, but no study to date has analyzed the
Kwang Il Nam +6 more
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Background: Magnetic resonance imaging (MRI) studies reported pineal gland atrophy in schizophrenia patients and individuals at a clinical high risk of developing psychosis, implicating abnormalities in melatonin secretion in the pathophysiology of ...
Tsutomu Takahashi +11 more
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The pineal gland and reproduction [PDF]
The hormonal activity of the pineal gland is influenced by both the dark-light cycle and the seasonal cycle, causing it to play an important role in the neuroendocrine control of reproductive physiology. This is especially evident in seasonally breeding animals, in which reproductive function is clearly influenced by seasonal variations in the duration
ALEANDRI, Vincenzo +2 more
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PRE-NATAL DEVELOPMENT OF THE PINEAL GLAND OF ALBINO RAT [PDF]
The pre-natal development of the pineal gland of albino rats was studied. In 131/2 days old-embryo, the pineal gland ap < /strong>peared as an evagination from the floor of the third ven tricle.
R.S. MOHAMMED +3 more
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