Results 21 to 30 of about 64,266 (267)
The role of melatonin in the development of postmenopausal osteoporosis
Frontiers in Pharmacology, 2022 Melatonin is an important endogenous hormone that modulates homeostasis in the microenvironment. Recent studies have indicated that serum melatonin levels are closely associated with the occurrence and development of osteoporosis in postmenopausal women.
Keda Yang +3 more
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The International Journal of Biochemistry & Cell Biology, 2006 Melatonin, originally discovered as a hormone of the pineal gland, is produced by bacteria, protozoa, plants, fungi, invertebrates, and various extrapineal sites of vertebrates, including gut, skin, Harderian gland, and leukocytes. Biosynthetic pathways seem to be identical.
Hardeland, Ruediger +2 more
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Melatonin Modulates the GABAergic Response in Cultured Rat Hippocampal Neurons
Journal of Pharmacological Sciences, 2012 In the present study, we investigated the effect of melatonin on the GABA-induced current (IGABA) and GABAergic miniature inhibitory postsynaptic currents (mIPSCs) in cultured rat hippocampal neurons using the whole-cell patch-clamp technique.
Xin-Ping Cheng +3 more
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Folia Medica, 2021 Epilepsy is a chronic neurological disease with recurrent seizures. Its incidence, the social and psychological aspects of epilepsy-associated stigmatization in society, the medical risk of severe seizures, and the challenges in treatment confirm its medical and social significance.
openaire +3 more sources
Melatonin distribution reveals clues to its biological significance in basal metazoans.
PLoS ONE, 2012 Although nearly ubiquitous in nature, the precise biological significance of endogenous melatonin is poorly understood in phylogenetically basal taxa.
Modi Roopin, Oren Levy
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Molecular Pain, 2022 The devastating chronic central post stroke pain is associated with variety of comorbidities. Disrupted sleep is a severe comorbidity, causing an increase in the suicide rate, due to CPSP’s pain symptom.
Tavleen Kaur +3 more
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Effects of Duodenal 5-Hydroxytryptophan Perfusion on Melatonin Synthesis in GI Tract of Sheep
Molecules, 2021 The purpose of this study is to investigate the potential effects of 5-hydroxytryptophan (5-HTP) duodenal perfusion on melatonin (MT) synthesis in the gastrointestinal (GI) tract of sheep.
Jun Pan +9 more
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Frontiers in Physiology, 2023 Introduction: Melatonin (5-methoxy-N-acetyl-tryptamine) is a circadian hormone synthesized and secreted by the pineal gland. In addition to regulating circadian rhythms of many physiological functions, melatonin is involved in regulating autonomic ...
Qiyao Yu +9 more
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Melatonin regulates gene expressions through activating auxin synthesis and signaling pathways
Frontiers in Plant Science, 2022 BackgroundBoth melatonin and indole-3-acetic acid (IAA) are derived from tryptophan. And the most interesting and unsolved puzzle in melatonin research is that what is the relationship between melatonin and auxin?MethodsIn this study, we performed ...
Wei Wei +6 more
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Biomedical Journal, 2016 Background: Continuous light or darkness has various effects on different systems. In the present research work, the effects of constant light and darkness exposure of male rats and oral administration of exogenous melatonin on the serum levels of ...
Naser Farhadi +2 more
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