Results 81 to 90 of about 403,757 (309)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

PRICE RISK MANAGEMENT IN WHITE CORN PRODUCTION [PDF]

open access: yes
White corn garners a premium over commodity corn, but suffers from additional price risk and yield drag. Using a simple bootstrap procedure, this research considers whether white corn premiums compensate for yield drag and evaluates the relative merits ...
Li, Lining, Pritchett, James G.
core   +1 more source

Brown Mid-Rib Corn Variety Trial [PDF]

open access: yes, 2014
Brown mid-rib (BMR) corn has a lower lignin content than other silage corn varieties, which makes it more digestible to dairy cows, potentially increasing milk production.
Cummings, Erica   +4 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Brown Mid-Rib Corn Population Trial [PDF]

open access: yes, 2012
Brown mid-rib (BMR) corn hybrids are of interest to many growers in the Northeast who would like to maximize milk production on homegrown forage. BMR corn has a naturally-occurring genetic mutation that leads to less lignin in the stalk and makes corn ...
Cummings, Erica   +4 more
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

RISK AND RETURN TO IP GRAIN PRODUCTION: THE CASE OF HIGH OIL CORN [PDF]

open access: yes
Returns for soybeans, commodity corn and high oil corn under an export and domestic market buyer's-call contract were simulated. High oil corn is competitive with commodity corn when yield drag is two percent and bundling reduces seed cost.
Davis, Todd D.   +2 more
core   +1 more source

Corn Yield Response to Plant Populations

open access: yesKansas Agricultural Experiment Station Research Reports, 2015
Corn hybrid development with a focus on drought tolerance has emerged in recent years, and producers have questions about their yield performance across a range of plant populations. A two-year study was conducted to determine the yield of corn hybrids across several plant populations. Corn hybrids responded differently in 2013 and 2014.
D. E. Shoup, E. A. Adee, I. A. Ciampitti
openaire   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

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