Results 131 to 140 of about 163,458 (264)

Selective γ8 transmembrane α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor regulatory protein negative allosteric modulators: Efficacy in preclinical antiseizure models

Epilepsia, EarlyView.
Abstract Objective RAP‐219, a potent selective negative allosteric modulator (NAM) of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) associated with γ8 transmembrane AMPAR regulatory protein (TARPγ8), is in phase 3 development for refractory focal epilepsy. This study was undertaken to assess efficacy and motor function following
Jose A. Matta, Brock T. Shireman, Laurie P. Volak, Michael P. Maher, Michael K. Ameriks, David Bredt   +5 more
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

The Demodex Expert Panel on Treatment and Eyelid Health (DEPTH) Consensus Regarding the Preferred Treatment for Demodex Blepharitis

Clinical Ophthalmology
Eric Donnenfeld,1 Kelly K Nichols,2 Brandon D Ayres,3 Marjan Farid,4 Preeya K Gupta,5,6 Richard Lyndon Lindstrom,7 Stephen Pflugfelder,8 Christopher E Starr,9 Nandini Venkateswaran,10 Ian Benjamin Gaddie,11 Paul M Karpecki,12 Cecelia Koetting,13 Selina ...
Donnenfeld E, Nichols KK, Ayres BD, Farid M, Gupta PK, Lindstrom RL, Pflugfelder S, Starr CE, Venkateswaran N, Gaddie IB, Karpecki PM, Koetting C, McGee S, Periman LM, Yeu E   +14 more
doaj  

Trendelenburg positioning with or without norepinephrine infusion for haemodynamic support in anaesthetised hypovolemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape, Klaus Hopster, Ismar Lutvikadic, Bernd Driessen   +3 more
wiley   +1 more source

Ueber das vordere Epithel der Cornea

, 1870
UEBER DAS VORDERE EPITHEL DER CORNEA Archiv für Anatomie, Physiologie und wissenschaftliche Medicin (-) Archiv für Anatomie, Physiologie und wissenschaftliche Medicin (-) Ueber das vordere Epithel der Cornea (-
Krause, W.
core   +1 more source

Del Cheratocono o cornea conica

DEL CHERATOCONO O CORNEA CONICA Franciscus Cornelius Donders Library (-) Del Cheratocono o cornea conica (3) (-
Quadri, Alessandro
core   +1 more source

The mean shape of the human cornea

, 1982
The anterior surface of the cornea is the major refracting element in the human eye. Knowledge of its shape and the variation of this shape throughout the population are important in calculations of the corneal contribution to ocular aberrations.
Smith, George, Carney, Leo G., Kiely, Patricia M.   +2 more
core  

Protective effects of adiponectin receptor agonists against equine lamellar endoplasmic reticulum stress

Equine Veterinary Journal, EarlyView.
Abstract Background Lamellar endoplasmic reticulum (ER) stress occurs in hyperinsulinemia‐associated and sepsis‐related laminitis. Adiponectin is associated with reduced laminitis risk and inhibits ER stress in other species. Objectives To induce ER stress in ex vivo equine lamellar cells using pharmacological agents.
Marine A. Barnabé, Jonathan Elliott, Nicola J. Menzies‐Gow, Simon R. Bailey, Nicholas J. Bamford, Yu‐Mei Chang, Matthew C. Gage   +6 more
wiley   +1 more source

The influence of a systemic non‐steroidal anti‐inflammatory drug on growth factors and cytokines in equine plasma, solid platelet‐rich fibrin (PRF), and liquid PRF

Equine Veterinary Journal, EarlyView.
Abstract Background Platelet‐rich fibrin (PRF) is a second‐generation platelet concentrate that contains growth factors and cytokines within a fibrin matrix, allowing prolonged release and supporting its use as a regenerative therapy for corneal wound healing.
Katrina E. V. Jones, Kimberly Young, Erin Barr, Chongben Zhang, Cody McGrath, Kimberly R. Love, Brian Gilger, Michala de Linde Henriksen   +7 more
wiley   +1 more source

Annona squamosa: Phytochemical Fingerprinting, Health‐Improving Traits, and Functional Applications

Food Chemistry International, EarlyView.
Annona squamosa (custard apple) is a nutrient‐rich fruit containing diverse bioactive phytochemicals (e.g., acetogenins, flavonoids, and alkaloids) that contribute to multiple health benefits, including antioxidant, antihyperlipidemic, and antimicrobial activities, highlighting its potential as a functional food and medicinal resource.
Mohamed Fawzy Ramadan, Jumanah Reda Kurdi, Manar Yahya Alzahrani, Asmaa Ibrahim Alshaikhi, Jumanah Samir Hazzazi   +4 more
wiley   +1 more source