Results 211 to 220 of about 305,787 (351)

Targeting Connexin 43 in Retinal Astrocytes Promotes Neuronal Survival in Glaucomatous Injury

open access: yesGlia, EarlyView.
Astrocytes play an important role in glaucoma. These cells express Cx43, which can form gap junctions and hemichannels. This study shows that Cx43 deletion in astrocytes provides neuroprotection in glaucoma, possibly through hemichannel activation. ABSTRACT Astrocytes in the retina and optic nerve head play an important role in the pathogenesis of ...
Khulan Batsuuri   +4 more
wiley   +1 more source

Computational models for generating microvascular structures: Investigations beyond medical imaging resolution

open access: yesWIREs Mechanisms of Disease, Volume 15, Issue 1, January/February 2023., 2023
Abstraction of the formation of new vascular connections through angiogenesis. Abstract Angiogenesis, arteriogenesis, and pruning are revascularization processes essential to our natural vascular development and adaptation, as well as central players in the onset and development of pathologies such as tumoral growth and stroke recovery.
Cameron Apeldoorn   +3 more
wiley   +1 more source

Mechanistic Insights and Pharmacological Approaches for Nitrogen and Sulfur Mustards and Their Implications as Therapeutic Agents

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Nitrogen and sulfur mustards, often acting as vesicants, have significant consequences for public health. Skin is a common site for exposure to these vesicants that can result in considerable morbidity and mortality. Given that the treatment options are limited, new insights into the mechanisms for the toxicity of these vesicants that can be ...
Madison Owens   +3 more
wiley   +1 more source

Stress induced aging in mouse eye

open access: yesAging Cell, Volume 21, Issue 12, December 2022., 2022
Skowronska‐Krawczyk and colleagues describe the transcriptional and epigenetic changes happening in aging retina. They also show that upon stress such as intraocular pressure elevation in the eye, retinal tissue undergoes epigenetic and transcriptional changes similar to natural aging.
Qianlan Xu   +15 more
wiley   +1 more source

An Improved Monte Carlo Method for Quantitative Analysis of Transparency Degradation Caused by Corneal Edema. [PDF]

open access: yesTransl Vis Sci Technol
Li S   +8 more
europepmc   +1 more source

Microsaccades Tracking by Secondary Speckle Pattern Analysis

open access: yesJournal of Biophotonics, EarlyView.
A new approach for detecting microsaccades is introduced using secondary speckle patterns reflected from the sclera. This method offers potential benefits in capturing subtle eye movements and overcoming limitations in traditional pupil‐tracking systems.
Ola Shteinberg   +6 more
wiley   +1 more source

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