Results 51 to 60 of about 5,158 (177)

Corneal Biomechanical Assessment Using Corneal Visualization Scheimpflug Technology in Keratoconic and Normal Eyes

open access: yesJournal of Ophthalmology, 2014
Purpose. To compare the corneal biomechanical properties of keratoconic patients and age-matched controls using corneal visualization Scheimpflug technology (Corvis ST). Methods. Sixty keratoconic eyes from 47 keratoconus patients and 60 normal eyes from
Lei Tian   +7 more
doaj   +1 more source

Changes in Stress-Strain Index in School-Aged Children: A 3-Year Longitudinal Study

open access: yesJournal of Ophthalmology, 2023
Purpose. To determine three-year change of the corneal biomechanical parameter stress-strain index (SSI) in schoolchildren aged 7– 9 years and their correlation with refractive error and axial length (AL). Methods.
Zhengfei Yang   +9 more
doaj   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

open access: yesAdvanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan   +13 more
wiley   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

open access: yesBMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang   +6 more
wiley   +1 more source

Association Between Corneal Biomechanical Properties and Glaucoma Severity [PDF]

open access: yesAmerican Journal of Ophthalmology, 2012
To investigate the association between corneal biomechanical parameters using the Ocular Response Analyzer (ORA) and glaucoma severity.Observational cross-sectional study.Two hundred ninety-nine eyes of 191 patients with confirmed or suspect glaucoma were recruited at the University of California, San Diego.
Kaweh, Mansouri   +5 more
openaire   +2 more sources

A Review of Artificial Intelligence in Ophthalmology: Key Aspects, Challenges, and Future Directions

open access: yesEye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is increasingly reshaping ophthalmology because the specialty depends heavily on structured imaging, quantitative measurements, and repeatable diagnostic workflows. This review provides a clinically grounded and translationally oriented synthesis of AI in ophthalmology, covering methodological foundations ...
Partha Pratim Ray
wiley   +1 more source

In Vivo Biomechanical Response of the Human Cornea to Acoustic Waves

open access: yesOptics, 2023
The cornea is the optical window to the brain. Its optical and structural properties are responsible for optical transparency and vision. The shape, elasticity, rigidity, or stiffness are due to its biomechanical properties, whose stability results in ...
Francisco J. Ávila   +2 more
doaj   +1 more source

Engineering Extracellular Vesicles: Strategies for Functional Modification and Clinical Translation

open access: yesiNew Medicine, EarlyView.
The engineering modification strategies of extracellular vesicles (EVs). This figure presents the four core technical systems for the engineering modification of EVs, including direct modification strategies (physical and chemical methods), biological engineering methods, and hybrid and bionic strategies.
Zhouming Cheng   +3 more
wiley   +1 more source

To Evaluate Corneal Biomechanical Changes after Strabismus Surgery with Ocular Response Analyzer

open access: yesBeyoglu Eye Journal, 2018
INTRODUCTION[|]Corneal biomechanical changes were also suspected and investigated after some scleral procedures but not after strabismus surgery. In this study we aimed to evaluate corneal biomechanical changes following strabismus procedures.with ocular
Ebru Demet Aygıt   +4 more
doaj   +1 more source

Fiber Bragg Grating Force Sensors for Minimally Invasive Surgery: State of the Art, Challenges, and Opportunities

open access: yesSmartBot, EarlyView.
This article reviews the application of fiber Bragg grating (FBG) technology for precise force sensing in minimally invasive surgery. It outlines the fundamental working principles and algorithms used to interpret sensor data. The text surveys clinical applications across various medical fields, such as ophthalmology and vascular intervention (Table of
Shiyuan Dong   +9 more
wiley   +1 more source

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