Results 171 to 180 of about 9,890 (252)

Simultaneous versus sequential corneal cross-linking and intracorneal ring segments implantation for keratoconus: two-year study. [PDF]

Int J Ophthalmol
Omar I, Safwat Elhiny R.
europepmc   +1 more source

Quality Evaluation Considerations for Stem Cell‐Derived Extracellular Vesicles‐Based Therapeutic Products in China

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT Stem cell therapy is currently undergoing clinical research in China for conditions that are resistant to or incurable by traditional pharmaceutical interventions. Stem cell‐derived extracellular vesicles (EVs) exhibit therapeutic effects similar to those of their parent stem cells, positioning them as an alternative or adjunctive approach to ...
Tao Na, Kehua Zhang, Libo Zhao, Xuanbao Yao, Chongfeng Xu, Yuan Zhang, Lan Wang, Miao Xu, Hui Zhang, Shufang Meng   +9 more
wiley   +1 more source

Effects of customized corneal cross-linking on higher-order aberrations in progressive keratoconus and low-grade myopia. [PDF]

Acta Ophthalmol
Hayek J, Viberg A, Elving S, Fredriksson A, Behndig A.   +4 more
europepmc   +1 more source

mRNA Lipid Nanoparticles for Cell Engineering in Vivo and in Vitro: Current Applications and Future Directions

MedComm, Volume 7, Issue 5, May 2026.
Schematic diagram of mRNA‐lipid nanoparticles (mRNA‐LNP) and its functional mechanisms, applications, and challenges in cell engineering. This figure details the structural composition of mRNA‐LNPs and the delivery strategy, highlighting three core challenges.
Lina Li, Menglan Wang, Xiuhan Ye, Zhiyan Liu, Yijing Duan, Xiaoming Chen, Yue Ouyang, Qibiao Wu, Mengjuan Sun, Tian Xie   +9 more
wiley   +1 more source

Determining the Relationship Between Corneal Stiffening and Tissue Dehydration After Corneal Cross-Linking. [PDF]

Invest Ophthalmol Vis Sci
Rodríguez-López R, Webb JN, Erdi M, Kofinas P, Franco W, Zhang H, Randleman JB, Scarcelli G.   +7 more
europepmc   +1 more source

RNA Modifications: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 5, May 2026.
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao, Tingwen Xiang, Chuan Yang, Xiaohua Wang, Gang Huang, Fei Luo, Zhao Xie, Yueqi Chen   +7 more
wiley   +1 more source

A Novel Oxygen Chamber for Corneal Cross-Linking in a High-Oxygen Environment: A Pilot Study and Clinical Outcomes. [PDF]

J Curr Ophthalmol
Alipour F, Abbas H, Kealamakia BE, Ashrafi E, Hafezi F, Beheshtnejad AH, Ghaffari R, Dehghani S.   +7 more
europepmc   +1 more source

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

MedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

Efficacy and Safety of Epi-On vs Epi-Off Corneal Cross-Linking in Corneal Ectasia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Clin Ophthalmol
Nughays RO, Bazayd AS, Alshamekh LA, Alshammari RA, Alenezi MA, Dahlan HY, Alsubhi JA, Alshammri SG, AlQurashi NA, Aldajani AH, Alrammah AH, Alenezi MN, Almutairi AA, Alomayri AF, Alghamdi S.   +14 more
europepmc   +1 more source

Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management

MedComm, Volume 7, Issue 5, May 2026.
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang, Zijiao Tian, Zhaoquan Wang, Zerui Yang, Ziyao Wang, Zikang Wang, Ziqing Wang, Xingyuan He, Yu Yan, Yuanfeng Gong, Siyuan Xu, Xinyi Li, Guihua Tian   +12 more
wiley   +1 more source