Results 91 to 100 of about 276,917 (287)

Effect of ageing on keratoconic corneas

Journal of Optometry, 2016
Purpose: To explore the potential effect of ageing on the corneal curvature and corrected visual acuity in patients with long-term keratoconus because of the paucity of these patients older than 50 years. Methods: Records of keratoconic patients, who had
Michel Millodot, Ilya Ortenberg, Karen Lahav-Yacouel, Shmuel Behrman   +3 more
doaj   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

The Multiple Criteria Qualitative Value‐Based Pricing Framework “MARIE” for Novel Cell and Gene Therapy

Clinical Pharmacology &Therapeutics, EarlyView.
When setting the price of cell and gene therapies in Japan, the factors considered include the manufacturing and operating costs of the new drug or a comparator, leading to discrepancies between price and values, in particular those specific to cell and gene therapies.
Akina Takami, Ataru Igarashi
wiley   +1 more source

Increased Corneal Toricity after Long-Term Orthokeratology Lens Wear

Journal of Ophthalmology, 2018
Purpose. To investigate the change in corneal toricity and associated refractive astigmatism after discontinuation of long-term orthokeratology (ortho-k) lens wear. Methods. This study investigated 136 subjects aged between 6 and 14 (9.1 ± 1.5) years old
Zhi Chen, Jiaqi Zhou, Feng Xue, Xingtao Zhou, Xiaomei Qu   +4 more
doaj   +1 more source

The relationship between central corneal thickness and corneal curvature in adult Nigerians

African Vision and Eye Health, 2011
Purpose: The aim of this study was to provide average values for central corneal thickness (CCT) and corneal curvature (CC) and also to determine a regression model for the relationship between CCT and CC in adult Nigerians without glaucoma. Methods: A
E. Iyamu, N. M. Eze
doaj   +1 more source

Low‐Dimensional Materials and Van Der Waals Heterostructures for Energy Application: A Comprehensive Review

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Low‐dimensional materials (0D, 1D, and 2D) exhibit unique electronic and physicochemical properties, enabling advanced nanoelectronic and optoelectronic devices. Mixed‐dimensional heterostructures combine these materials to enhance functionality.
Qaisar Alam, Sajjad Ali, Pir Muhammad Ismail, ABM Sharif Hossain   +3 more
wiley   +1 more source

Artificial Intelligence in Ophthalmology: From Methodological Advances to Clinical Translation and Future Directions

Eye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is reshaping ophthalmology from task‐specific image analysis toward multimodal, longitudinal, and clinically integrated decision support. This narrative review summarizes the methodological evolution of ophthalmic AI, including traditional machine learning, task‐specific deep learning, self‐supervised learning ...
Yuxin Liu, Hanruo Liu
wiley   +1 more source

Regulation of corneal stromal cell behavior by modulating curvature using a hydraulically-controlled organ chip array

Nature Communications
Corneal curvature abnormalities drive ectatic diseases, yet their mechanobiological effects on stromal cells remain poorly understood. We developed a hydraulically controlled curvature array chip recapitulating disease-relevant geometries (33-56D) to ...
Minju Kim, Kanghoon Choi, David Križaj, Jungkyu Kim   +3 more
doaj   +1 more source

Comparison of Corneal Parameters of Children with Diabetes Mellitus and Healthy Children

Journal of Ophthalmology, 2019
Purpose. To compare differences in central corneal thickness (CCT), corneal curvature, and other corneal measurements of children with diabetes mellitus (DM) and healthy children, and to investigate related factors. Methods. This was a case-control study.
Shanshan Wang, Yan Jia, Tao Li, Anken Wang, Lu Gao, Chenhao Yang, Haidong Zou   +6 more
doaj   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source