Results 61 to 70 of about 276,917 (287)
Advanced Science, EarlyView.Ex‐spRandom is a spatial transcriptomics platform that synergizes random‐primed chemistry with iterative hydrogel expansion. By physically decrowding the dense FFPE matrix, this scalable technology shatters the traditional resolution‐sensitivity barrier.
Shunji Zhang +7 more
wiley +1 more source
Bacterial synthesis of personalized biomimetic biological cornea
Bioactive MaterialsCorneal transplantation is one of the most effective treatments for corneal blindness. However, aside from clinical donor shortage, matching the transparency, curvature, and mechanical properties of artificial corneal materials with autologous corneas is
Liyin Wang +13 more
doaj +1 more source
Advanced Science, EarlyView.Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu +20 more
wiley +1 more source
OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD
Advanced Science, EarlyView.This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li +11 more
wiley +1 more source
Kerala Journal of Ophthalmology, 2016 Context: Central corneal thickness (CCT) was assumed to be a constant when Goldmann designed his applanation tonometer. Knowledge of the CCT is of importance in the assessment of intraocular pressures (IOPs).
Vivek Oommen Varghese +5 more
doaj +1 more source
Advanced Science, EarlyView.This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree +18 more
wiley +1 more source
THE RELATION OF CORNEAL CURVATURES TO THE REFRACTION OF THE EYE. [PDF]
JAMA: The Journal of the American Medical Association, 1905 I have included in this report all cases of refraction examined under a cycloplegic that came under my care from December, 1901, to December, 1903. The errors of refraction were estimated in the usual manner with trial lenses. The instrument used in making the corneal measurements was the ophthalmometer of Chambers, Inskeep & Co.
openaire +1 more source
A survey of corneal curvature changes from corneal lens wear
, 1997 The fact that variations in corneal curvature occur as a result os wearing PMMA contact lenses has been reported many times (1-8). The nature of these curvature changes and the factors influencing them are, however, still not well defined.
Bailey, Ian L., Carney, Leo G.
core
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Values of refractive error, corneal curvature, astigmatism and central thickness.
, 2013 SE = refractive error and converted to spherical equivalent, Km = mean corneal curvature (the mean of corneal curvature in horizontal and vertical axis); CA = corneal astigmatism (the difference between corneal curvature in horizontal and vertical axis);
Qinmei Wang (132105) +7 more
core +1 more source